2017—2019年天津儿童医院口服抗组胺药使用情况分析

目的 了解天津市儿童医院口服抗组胺药的使用情况，为临床药品管理和合理用药提供参考。方法 收集天津市儿童医院2017-2019年门诊药房口服抗组胺药品的相关数据信息，统计药品用药金额、用药频度（DDDs）、日均费用（DDC），并分析其变化趋势。结果 2018、2019年口服抗组胺药的使用量和用药金额相对平稳，但相对于2017年的使用量和用药金额则均有大幅提升，第1代抗组胺药的用药金额占比不到全部抗组胺药的1%，3年来，抗组胺药的用药频度（DDDs）排在第1位的药品是盐酸左西替利嗪片，日均费用（DDC）最高的药品是氯雷他定糖浆。结论 天津市儿童医院抗组胺药的使用量和用药频率与患儿年龄特征和儿童过敏性疾病的发病率密切相关，其临床应用基本合理，同时应及时了解临床用药现状，规范管理，合理用药。

Analysis on use of oral antihistamines in Tianjin Children's Hospital from 2017 to 2019

Objective To understand the use of oral antihistamines in Tianjin Children''s Hospital, and provide a reference for clinical drug management and rational drug use. Methods The relevant data of oral antihistamine drugs were collected in outpatient pharmacies of Tianjin Children''s Hospital from 2017 to 2019, and sales amount, frequency of drug use (DDDs), and daily average drug cost (DDC) were statistically counted to analyze their changes. Results The use and amount of oral antihistamines in 2018 and 2019 were relatively stable, but compared to 2017, the use and amount of drugs were significantly increased. The amount of first-generation antihistamines accounted for less than 1% of the total antihistamines. For the past three years, the drug with the highest frequency of application of antihistamines has been Levoctirizine Hydrochloride Tablets, the drug with the highest average daily cost of applying antihistamines was Loratadine Syrup. Conclusion The amount and frequency of antihistamines in Tianjin Children''s Hospital are closely related to the age characteristics of children and the incidence of allergic diseases in children. Its clinical application is basically reasonable. At the same time, the current status of clinical medication should be timely understood and strived to achieve standardized management and rational use of medication.