Methods and prognosis of the extirpation of pulmonary metastases following tumor nephrectomy |
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Authors: | G Schott J Weissmüller E Vecera |
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Institution: | Department of Urology, University Hospital of Erlangen, FRG. |
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Abstract: | Nephrectomy was performed in 938 patients with renal carcinoma between the years 1960 and 1986. The cumulative survival rate was 78.7 +/- 2.7% after 1 year; 62.9 +/- 3.2% after 3 years; 52.4 +/- 3.5% after 5 years, and 38.0 +/- 4.1% after 10 years. Of this group, 39 patients with lung metastases underwent surgery of their metastases following radical surgical removal of their primary tumor. Using the so-called actuarial method of analysis, the cumulative survival rate of this group was 66.7 +/- 15.1% 1 year after the lung surgery; 47.6 +/- 16.3% after 3 years and 32.7 +/- 15.7% after 5 years. The survival rates were correlated with the number of metastases, the operative techniques employed, and with the time interval between primary tumor removal and the appearance of secondary lung metastases. A comparison was made between those patients who underwent curative lung surgery (R0 group) and those with residual tumor (R+ group). Follow-up of the tumor status at the end of the study of the 39 patients is presented. |
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