胃肠道类癌临床病理分析

目的探讨胃肠道类癌的临床、病理学特点及诊断要点。方法收集13例胃肠道类癌标本,全部标本经H-E切片及免疫组化染色观察,并对13例患者进行术后随访。结果所有患者均接受手术治疗并经病理H-E切片及免疫组化染色证实为胃肠道类癌,包括胃底贲门部1例,胃窦部2例,阑尾盲端4例,回肠4例,直肠2例。随访情况:3例失访,1例胃窦部类癌及2例回肠类癌由于术后复发和广泛转移2年内死亡,其中1例回肠类癌存活11个月,其余7例随访3~6年至今健在。结论胃肠道类癌的诊断主要靠病理H-E切片及免疫组化染色,其预后与肿瘤的大小、发生部位、组织形态类型、分化程度、浸润深度、转移情况等有关,治疗以手术切除为主。

Clinicopathologic Study of Gastrointestinal Carcinoid Tumors

Objective To explore the clinical and pathologic characteristics,diagnostic methods for gastrointestinal carcinoid tumors (GICT).Methods 13 cases of GICT were analysized with HE,immunohistochemical stainings from 1988 to 2004 specimens.All of the patients would be follow-up after operation.Results All of the patient s with GICT including cardia in 1,pylorus in 2,appendix in 4,intestinal in 4,colonic in 2,were treated by surgical excision and confirmed by biopsy at endoscopy or surgery.During our follow-up three cases of GICT were dead by recurrence and metastasize.The other seven cases were still living now.Conclusion The diagnosis depends mainly on HE as well as immunohistochemical staining.The prognosis depends on tumor size,differentiation,infiltration and local lymph node invasion.Operation may be the first choice for such patients.