Acute renal failure due to a malignant lymphoma infiltration uncovered by renal biopsy. |
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| Authors: | Lorenz Sellin Cornelia Friedl Guido Klein Rüdiger Waldherr L Christian Rump Stefan M Weiner |
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| Institution: | Department of Nephrology, Medicine I, Marienhospital Herne, Hospital of the University of Bochum, H?lkeskampring 40, D-44625 Herne, Germany. |
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| Abstract: | |
Introduction
| Renal involvement by large B-cell lymphoma represents an exceptionalmanifestation of non-Hodgkin lymphoma. Acute renal failure (ARF)by a lymphoma infiltration of the kidney is extremely rare (sofar 11 cases have been reported in the literature). We reporta patient who was hospitalized for upper GI bleeding. Clinicalexamination revealed a tumour of the os sacrum. A CT-guidedneedle biopsy led to the diagnosis of a sarcoma. At this time,progressive renal failure was observed. Ultrasound showed enlargedkidneys with normal arterial and venous perfusion conditions.No urinary tract obstruction was detected. The cause of ARFwas diagnosed by renal biopsy to be a diffuse infiltration ofa large B-cell non-Hodgkin lymphoma. The re-evaluation of theprimary histology of the os sacrum confirmed the renal biopsydiagnosis of the B-cell lymphoma. Subsequent staging showedan additional lymphoma infiltration of the lung and liver,
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| Keywords: | acute renal failure large B-cell non-Hodgkin lymphoma renal biopsy renal lymphoma infiltration |
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