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前列地尔联合红花黄色素治疗老年慢性肾衰竭的临床观察
引用本文:林崇亭,吴达改,李波. 前列地尔联合红花黄色素治疗老年慢性肾衰竭的临床观察[J]. 解放军保健医学杂志, 2011, 0(3)
作者姓名:林崇亭  吴达改  李波
作者单位:龙口市人民医院内二科;龙口市兰高中心卫生院;
摘    要:目的观察注射用前列地尔联合红花黄色素治疗老年慢性肾衰竭(CRF)的临床疗效。方法选择50例老年CRF患者随机分为治疗组(26例)和对照组(24例)。在常规治疗的基础上,治疗组加注射用前列地尔和注射用红花黄色素治疗,对照组仅予常规治疗,观察两组患者治疗前后血清尿素(BUN)、肌酐(SCr)、肌酐清除率(Ccr)、24h尿蛋白定量(24hUp)及血液流变学参数的变化。结果治疗组治疗两周时BUN为(11.25±6.01)mmol/L、SCr为(318.04±90.50)μmol/L、24hUp为(1.45±1.06)g较治疗前的(16.35±6.05)mmol/L、(390.60±99.56)μmol/L、(1.90±1.21)g显著降低(P<0.05),Ccr为(29.18±16.26)ml/min,较治疗前的(21.64±10.20)ml/min显著升高(P<0.05),血液流变学参数较治疗前显著改善(P<0.05);治疗4周时以上指标较治疗前显著改善(P<0.05)。对照组治疗前后各观测指标比较差异无统计学意义。治疗中未发生严重不良反应。结论老年CRF患者在常规治疗的基础上,应用前列地尔联合红花黄色素是一种安...

关 键 词:慢性肾衰竭  前列地尔  红花黄色素  老年  

Clinical study on the treatment of chroinc renal failure with alprostadil combined with safflower yellow in elderly cases
LIN Chong-ting,WU Da-gai,LI Bo. Clinical study on the treatment of chroinc renal failure with alprostadil combined with safflower yellow in elderly cases[J]. Journal Of Health Care And Medicine in Chinese Pla, 2011, 0(3)
Authors:LIN Chong-ting  WU Da-gai  LI Bo
Affiliation:LIN Chong-ting,WU Da-gai,LI Bo (Second Department of Internal Medicine,Longkou People's Hospital,Longkou 265701,China)
Abstract:Objective To investigate the clinical effect of alprostadil injection combined with safflower yellow injection in the treatment of chroinc renal failure(CRF)in elderly cases. Methods Fifty elderly patients were randomly divided into treatment group(n=26)and control group(n=24). Alprostadil injection and safflower yellow injection were given based on the routine treatment of patients in treatment group,while only routine treatment was performed in the control group. Levels of blood urea nitrogen(BUN), serum ...
Keywords:Chroinc renal failure  Alprostadil  Safflower yellow  Eldly  
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