| 枸橼酸钠注射液细菌内毒素检查方法的考察 |
| |
| 引用本文： | 何进,史国兵,高军,陈金旺.枸橼酸钠注射液细菌内毒素检查方法的考察[J].解放军药学学报,2011,27(3):254-255. |
| |
| 作者姓名： | 何进 史国兵 高军 陈金旺 |
| |
| 作者单位： | 1. 沈阳军区总医院药剂科,辽宁沈阳,110840
2. 大连医科大学临床药学系,辽宁大连,116027 |
| |
| 摘 要： | 目的 建立枸橼酸钠注射液细菌内毒素检查方法.方法 按<中国药典>2005年版附录细菌内毒素检查法,分别进行了鲎试剂灵敏度复核试验、细菌内毒素干扰试验.结果 枸橼酸钠注射液稀释6倍后,不干扰鲎试剂与细菌内毒素的凝胶反应.结论 可用细菌内毒素检查法替代家兔法检查枸橼酸钠注射液中的细菌内毒素.
|
| 关 键 词： | 枸橼酸钠注射液 细菌内毒素检查 干扰试验 |
Studies of Bacterial Endotoxins Test of Sodium Citrate Injection |
| |
| HE Jin,SHI Guo-bing,GAO Jun,CHEN Jin-wang.Studies of Bacterial Endotoxins Test of Sodium Citrate Injection[J].Pharmaceutical Journal of Chinese People's Liberation Army,2011,27(3):254-255. |
| |
| Authors: | HE Jin SHI Guo-bing GAO Jun CHEN Jin-wang |
| |
| Institution: | ②①Department of Pharmacy,the General Hospital of Shenyang Military Region,Shenyang110840,China;②Dalian Medical University,Dalian116027,China |
| |
| Abstract: | Objective To establish a method of bacterial endotoxin test of sodium citrate injection by gel clot.Methods The method was based on the bacterial endotoxin test in the appendix of Chp 2005.A series of tests were performed,such as the sensitivity test of tachypleus amebocyte lysate,first interference test and interference tests.Results No interference was found after the sodium citrate injection was diluted 6 times in the bacterial endotoxin interference factors test.Conclusion The present method can replace... |
| |
| Keywords: | sodium citrate injection bacterial endotoxin test interference test |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
