中药联合高位结肠净化治疗老年慢性肾功能不全的观察

目的评价中药联合高位结肠净化治疗老年慢性肾功能不全的近期疗效及安全性。方法 23例老年慢性肾功能不全的患者进行自身对照试验,前4周给予常规内科治疗,后4周在内科治疗的基础上加用中药联合高位结肠净化治疗,观察治疗前后患者临床症状积分的变化,检测治疗前后血清尿素(BUN)、肌酐(SCr)、尿酸(UA)、K+、Na+、Cl-、Ca2+、P3+、二氧化碳结合力(CO2-CP)的变化以及便常规、肝功能、不良事件等安全性指标。结果内科治疗与加用中药联合高位结肠净化治疗临床症状积分分别较治疗前下降(1.67±1.52)分和(7.13±1.89)分,差异有统计学意义(P<0.01)。内科治疗治疗前后SCr、BUN、UA差异无统计学意义,加用中药联合高位结肠净化治疗后SCr下降(24.54±29.47)μmol/L(P<0.01),BUN下降(1.01±2.37)mmol/L(P<0.05),UA下降(30.13±46.20)μmol/L(P<0.01);两种方法及治疗前后SCr、BUN、UA差值比较,差异均有统计学意义(P<0.01)。肾小球滤过率水平,内科治疗前后差异不显著,加用中药联合高位结肠净化治疗后上升(1.51±3...

Clinical study on elderly patients with chronic renal failure of sequential colon purification with Chinese herbs

Objective To evaluation the safety and efficacy of colon purification with Chinese herbs in treatments of aging with chronic renal failure. Methods Twenty-three elderly cases with chronic renal failure were treated with internal medicine,or internal medicine plus colon purification with Chinese herbs respectively for 4 weeks. The indexes of efficacy,including symptom scores,serum creatinine(SCr),urea nitrogen(BUN),uric acid(UA)and eGFR,as well as the indexes of safety,including stool routine,liver function ...