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| 正交试验法优选芩榆烧伤液提取工艺研究 | |
| 引用本文： | 李维强,王云飞,苏庆,薛桂蓬,毛艳,贺金华.正交试验法优选芩榆烧伤液提取工艺研究[J].解放军药学学报,2011,27(4):293-295. |
| 作者姓名： | 李维强 王云飞 苏庆 薛桂蓬 毛艳 贺金华 |
| 作者单位： | 1. 842000 新疆库车,解放军69220部队医院 2. 新疆维吾尔自治区药物研究所, 新疆乌鲁术齐,830004 3. 总后勤部卫生部药品仪器检验所, 北京,100071 |
| 基金项目： | 新疆自治区高技术研究发展计划项目,No.201110105 |
| 摘 要： | 目的研究芩榆烧伤液提取工艺,优选最佳工艺条件。方法以黄芩苷含量为检测指标,用正交法考察3种因素(乙醇浓度、加醇倍量、渗漉速度)对含量的影响。结果黄芩苷在10.36~51.8μg/ml范围内线性关系良好(r=0.9993,n=5)。最佳提取工艺为A2B2C1,即30倍量60%乙醇,以7 ml/min的流速进行渗漉。结论该提取工艺设计合理,结果可靠,可用于芩榆烧伤液的制备。 |
| 关 键 词： | 芩榆烧伤液 渗漉法 提取工艺 正交试验 |
A Study on the Extraction Technology of Qinyu Solution for Burns |
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| LI Wei-qiang,WANG Yun-fei,SU Qing,XU E Gui-peng,MAO Yan,HE Jin-hua.A Study on the Extraction Technology of Qinyu Solution for Burns[J].Pharmaceutical Journal of Chinese People's Liberation Army,2011,27(4):293-295. | |
| Authors: | LI Wei-qiang WANG Yun-fei SU Qing XU E Gui-peng MAO Yan HE Jin-hua |
| Institution: | ②①69220 Military Hospital of PLA,Kuche842000,China;②Xinjiang Institute of Materia Medica,Urumqi830004,China;③Institute for Drug and Instrument Control of Health Dept GLD of PLA,Beijing100071,China |
| Abstract: | Objective To optimize the extraction process of Qinyu Solution for Burns.Methods The content of baicalin was adopted as the index and determined by high performance liquid chromatography.Orthogonal-test L9（34） was employed to optimize the extraction technology.Results The content of baicalin showed a good linear relationship within the range of 10.36-51.8 μg/ml（r=0.9993,n=5）.The optimal extraction technology was adding 30 times the amount of 60% alcohol at the extraction rate 7 ml/min.Conclusion This extraction technology is feasible and applicable for the preparation of Qinyu Solution for Burns. |
| Keywords: | Qinyu Solution for Burns percolation method extraction technology orthogonal experiment |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |