| 灵芝三萜对α-萘异硫氰酸酯致大鼠肝损伤的保护作用 |
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| 引用本文： | 张文晶,余明莲,吴楠.灵芝三萜对α-萘异硫氰酸酯致大鼠肝损伤的保护作用[J].解放军药学学报,2011,27(4):318-320,324. |
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| 作者姓名： | 张文晶 余明莲 吴楠 |
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| 作者单位： | 北京军区总医院妇产科, 北京,100700 |
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| 摘 要： | 目的 观察灵芝三萜对α-萘异硫氰酸酯所致大鼠急性黄疸模型的退黄降酶作用.方法 将Wistar大鼠随机分为正常组、α-萘异硫氰酸酯肝损伤模型组、灵芝三萜高、中、低( 200、100、50 mg/kg)剂量组和阳性药物组（赤丹退黄颗粒）.各治疗组大鼠连续灌胃给药7d,除正常对照组外,第4天给药后2h,各给药组及模型组灌胃给...
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| 关 键 词： | 灵芝三萜 α-萘异硫氰酸酯 肝损伤 黄疸 保肝作用 |
Effect of Ganoderma Triterpene on Reduced Jaundice and Enzyme in the Jaundice Model of Rats Induced by A-naphthyl Isothiocyanate |
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| ZHANG Wen-jing,YU Ming-lian,WU Nan.Effect of Ganoderma Triterpene on Reduced Jaundice and Enzyme in the Jaundice Model of Rats Induced by A-naphthyl Isothiocyanate[J].Pharmaceutical Journal of Chinese People's Liberation Army,2011,27(4):318-320,324. |
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| Authors: | ZHANG Wen-jing YU Ming-lian WU Nan |
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| Institution: | ZHANG Wen-jing,YU Ming-lian,WU NanDepartment of Obstetrics and Gynaecology,General Hospital of Beijing Military Command,Beijing100700,China |
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| Abstract: | Objective To observe the effect of Ganoderma Triterpeneon reducing jaundice and enzyme in jaundice model of rats induced by a-naphthyl isothiocyanate.Methods Rats were randomized into six groups: group A in which no treatment was given,group B in which a-naphthyl isothiocyanate was given,group C in which Chidantuihuang Granules were given as positive control,group D in which a low dosage(50 mg/kg) of Ganoderma Triterpene was given,group E in which a moderate dosage(100 mg/kg) of Ganoderma Triterpene was giv... |
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| Keywords: | Ganoderma Triterpene a-naphthyl isothiocyanate liver damage jaundice hepatoprotective effect |
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