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Tamoxifen is not effective in good prognosis patients with hepatocellular carcinoma
Authors:Ciro Gallo  Ermelinda De Maio  Massimo Di Maio  Giuseppe Signoriello  Bruno Daniele  Sandro Pignata  Annalisa Annunziata  Francesco Perrone
Affiliation:(1) Department of Medicine and Public Health, Second University, Naples, Italy;(2) Clinical Trials Unit, National Cancer Institute, Naples, Italy;(3) G. Rummo Hospital, Benevento, Italy;(4) Medical Oncology B, National Cancer Institute, Naples, Italy
Abstract:

Background  

Large randomised clinical trials and systematic reviews substantiate that tamoxifen is ineffective in improving survival of patients with hepatocellular carcinoma (HCC). However, a recent report suggested that the drug might prolong survival among patients with well preserved liver function. The aim of this paper is to validate this hypothesis.
Keywords:
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