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皮敏消胶囊联合糠酸莫米松乳膏治疗寻常型银屑病的效果
引用本文:宫经念.皮敏消胶囊联合糠酸莫米松乳膏治疗寻常型银屑病的效果[J].医学美学美容,2023,32(19):70-73.
作者姓名:宫经念
作者单位:公安县中医医院皮肤科
摘    要:的 探讨对寻常型银屑病患者采用皮敏消胶囊联合糠酸莫米松乳膏治疗的临床效果。方法 选 取公安县中医医院皮肤科2018年8月-2022年7月收治的100例寻常型银屑病患者为研究对象,通过随机 数字表法分为对照组和观察组,每组50例。对照组采用糠酸莫米松乳膏治疗,观察组采用皮敏消胶囊联 合糠酸莫米松乳膏治疗,比较两组中医症状积分、皮损严重程度、炎性因子水平及不良反应发生情况。 结果 观察组治疗后红斑瘙痒、烦躁乏力、舌红苔白评分及PASI评分均低于对照组(P<0.05);观察 组治疗后IL-10、IL-17水平均低于对照组(P<0.05);观察组不良反应发生率为2.00%,低于对照组的 18.00%(P<0.05)。结论 皮敏消胶囊联合糠酸莫米松乳膏治疗寻常型银屑病的效果良好,不仅能够有效 改善患者的临床症状,减轻其皮损严重程度,还能有效抑制炎性因子水平,降低不良反应的发生几率。

关 键 词:寻常型银屑病  皮敏消胶囊  糠酸莫米松乳膏  炎性因子

Effect of Piminxiao Capsule Combined with Mometasone Furoate Cream in the Treatment of Psoriasis Vulgaris
Authors:GONG Jing-nian
Institution:Department of Dermatology, Gong''an County Hospital of Traditional Chinese Medicine
Abstract:Objective To explore the clinical effect of Piminxiao capsule combined with mometasone furoate cream in the treatment of patients with psoriasis vulgaris. Methods A total of 100 patients with psoriasis vulgaris admitted to the Department of Dermatology of Gong''an County Hospital of Traditional Chinese Medicine from August 2018 to July 2022 were selected as the research objects. They were divided into control group and observation group by random number table method, with 50 patients in each group. The control group was treated with mometasone furoate cream, and the observation group was treated with Piminxiao capsule combined with mometasone furoate cream. The TCM symptom scores, severity of skin lesions, levels of inflammatory factors and adverse reactions were compared between the two groups. Results After treatment, the scores of erythema and itching, irritability and fatigue, red tongue and white tongue coating and PASI score in the observation group were lower than those in the control group (P<0.05). After treatment, the levels of IL-10 and IL-17 in the observation group were lower than those in the control group (P<0.05). The incidence of adverse reactions in the observation group was 2.00%, which was lower than 18.00% in the control group (P<0.05). Conclusion Piminxiao Capsules combined with mometasone furoate cream has a good effect in the treatment of psoriasis vulgaris. It can not only effectively improve the clinical symptoms of patients, reduce the severity of skin lesions, but also effectively inhibit the level of inflammatory factors and reduce the incidence of adverse reactions.
Keywords:Psoriasis vulgaris  Piminxiao capsules  Mometasone furoate cream  Inflammatory factors
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