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Risk factors associated with relapse after methotrexate dose reduction in patients with rheumatoid arthritis receiving golimumab and methotrexate combination therapy
Authors:Noboru Kitamura  Hitomi Kobayashi  Yosuke Nagasawa  Kaita Sugiyama  Hiroshi Tsuzuki  Yutaka Tanikawa  Natsumi Ikumi  Yuito Okada  Yasuo Takahashi  Satoshi Asai  Naoto Tamura  Michihiro Ogasawara  Toshio Kawamoto  Ryohei Kuwatsuru  Hiromichi Tamaki  Genki Kidoguchi  Mutsuto Tateishi  Makiko Kimura  Yuichi Mochida  Kengo Harigane  Takayuki Shimazaki  Takao Koike  Kazuhide Tanimura  Hiroshi Kataoka  Koichi Amano  Hidekata Yasuoka  Masami Takei
Affiliation:1. Department of Medicine, Division of Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan;2. Department of Dermatology, Nihon University School of Medicine, Tokyo, Japan;3. Clinical Trials Research Center, Nihon University School of Medicine, Tokyo, Japan;4. Department of Pharmacology and Biofunction Medicine, Nihon University School of Medicine, Tokyo, Japan;5. Internal Medicine and Rheumatology, Juntendo University Faculty of Medicine, Tokyo, Japan;6. Department of Radiology & Center for Promotion of Data Science, Juntendo University Graduate School of Medicine, Tokyo, Japan;7. Immuno-Rheumatology Center, St. Luke's International Hospital, Tokyo, Japan;8. Department of Rheumatology, Tokyo Metropolitan Ohtsuka Hospital, Tokyo, Japan;9. Center for Rheumatic Diseases, Yokohama City University Medical Center, Yokohama, Japan;10. Hokkaido Medical Center for Rheumatic Diseases, Sapporo, Japan;11. Department of Rheumatology and Clinical Immunology, Sapporo City General Hospital, Sapporo, Japan;12. Department of Rheumatology and Clinical Immunology, Saitama Medical Center Saitama Medical University, Saitama, Japan;13. Department of Internal Medicine, Division of Rheumatology, Fujita Health University School of Medicine, Toyoake, Japan
Abstract:
Keywords:anti-tumor necrosis factor  golimumab  methotrexate  relapse  rheumatoid arthritis
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