高通量血液透析治疗慢性肾衰竭尿毒症的效果及对免疫功能的影响

目的探讨高通量血液透析治疗慢性肾衰竭尿毒症的效果及对免疫功能的影响。方法选取本院80例慢性肾衰竭尿毒症患者为研究对象,按平行对照法分为研究组(n=40,高通量血液透析)与对照组(n=40,低通量血液透析)。比较两组治疗效果。结果治疗后,两组血肌酐、血尿素、β_2-MC、CysC水平均低于治疗前,且研究组低于对照组(P<0.05);研究组治疗总有效率显著高于对照组(P<0.05);治疗后,两组IgA、IgG、IgM水平均高于治疗前,且研究组高于对照组(P<0.05)。结论慢性肾衰竭尿毒症治疗中应用高通量血液透析,可清除毒素,改善免疫功能,促进康复。

Effect of high-throughput hemodialysis on chronic renal failure uremia and its influence on immune function

Objective To explore the effect of high throughput hemodialysis on chronic renal failure uremia and its influence on immune function.Methods Eighty cases of uremia in chronic renal failure treated in our hospital were divided into study group(n=40,high flux hemodialysis)and control group(n=40,low flux hemodialysis)by parallel control method.The treatment effects of the two groups were compared.Results After treatment,the levels of serum creatinine,blood urea,β2-MC and CysC in both groups were lower than those before treatment,and those of the study group were lower than the control group(P<0.05).The total effect rate of treatment in the study group was higher than that in the control group(P<0.05).After treatment,the levels of IgA,IgG and IgM in both groups were higher than those before treatment,and those in the study group were higher than the control group(P<0.05).Conclusion High-throughput hemodialysis in the treatment of uremia in chronic renal failure can remove toxins,improve immune function and promote rehabilitation.