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早期康复联合丁苯酞注射液治疗急性脑梗塞的效果及对肢体功能和日常生活能力的影响
引用本文:付智渊,王皓月. 早期康复联合丁苯酞注射液治疗急性脑梗塞的效果及对肢体功能和日常生活能力的影响[J]. 临床医学研究与实践, 2019, 4(9): 51-53
作者姓名:付智渊  王皓月
作者单位:陕西省府谷县人民医院,陕西 榆林,719499;陕西省府谷县人民医院,陕西 榆林,719499
摘    要:目的探讨早期康复联合丁苯酞注射液治疗急性脑梗塞的效果及对肢体功能与日常生活能力的影响。方法选择本科室80例急性脑梗塞患者为研究对象,按照随机数表法将患者分为常规组(n=40)和干预组(n=40)。常规组给予丁苯酞注射液治疗,干预组实施早期康复联合丁苯酞注射液治疗。比较两组患者的治疗效果。结果治疗2周后,两组超氧化物歧化酶及丙二醛水平均改善,且干预组优于常规组(P<0.05)。治疗2周后,两组肿瘤坏死因子-α及白细胞介素-6水平均降低,且干预组低于常规组(P<0.05)。治疗2周后,两组碱性成纤维细胞生长因子、脑源性神经营养因子水平均改善,且干预组优于常规组(P<0.05)。治疗2周后,两组上、下肢功能、日常生活能力评分及GOS评分均升高,且干预组高于常规组(P<0.05)。结论早期康复联合丁苯酞注射液治疗急性脑梗塞可有效抑制氧化应激反应及炎性因子水平,还可改善患者神经营养状态、肢体功能、日常生活能力及预后。

关 键 词:急性脑梗塞  早期康复  丁苯酞注射液  肢体功能  日常生活能力

Effect of early rehabilitation combined with butylphthalide injection in the treatment of acute cerebral infarction and the influence on limb function and activity of daily living
FU Zhi-yuan,WANG Hao-yue. Effect of early rehabilitation combined with butylphthalide injection in the treatment of acute cerebral infarction and the influence on limb function and activity of daily living[J]. Clinical Research and Practice, 2019, 4(9): 51-53
Authors:FU Zhi-yuan  WANG Hao-yue
Affiliation:(the People's Hospital of Fugu County,Yulin 719499,China)
Abstract:Objective To investigate the effect of early rehabilitation combined with butylphthalide injection in the treatment of acute cerebral infarction and the influence on limb function and activity of daily living.Methods Eighty patients with acute cerebral infarction in our department were selected as the study objects.The patients were divided into routine group(n=40)and intervention group(n=40)by random number table method.The routine group was treated with butylphthalide injection,while the intervention group was treated with early rehabilitation combined with butylphthalide injection.The therapeutic effects of the two groups were compared.Results After 2 weeks of treatment,the levels of superoxide dismutase and malondialdehyde improved in both groups,and those in the intervention group were better than the routine group(P<0.05).After 2 weeks of treatment,the levels of tumor necrosis factor-α and interleukin-6 in both groups decreased,and those in the intervention group were lower than the routine group(P<0.05).After 2 weeks of treatment,the levels of basic fibroblast growth factor and brain-derived neurotrophic factor in both groups improved,and those in the intervention group were better than the routine group(P<0.05).After 2 weeks of treatment,the scores of upper and lower limbs function,activity of daily living and GOS increased in both groups,and those in the intervention group were higher than the routine group(P<0.05).Conclusion Early rehabilitation combined with butylphthalide injection can effectively inhibit oxidative stress response and secretion of inflammatory factors in patients with acute cerebral infarction,and improve neurotrophic status,limb function,activity of daily living and prognosis.
Keywords:acute cerebral infarction  early rehabilitation  butylphthalide injection  limb function  activity of daily living
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