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激光诱发自体荧光光谱技术诊断鼠肝纤维化
引用本文:陈丹梅,赵钢,唐建武,李连宏,丁建华,高泽红,朱英. 激光诱发自体荧光光谱技术诊断鼠肝纤维化[J]. 中国激光医学杂志, 2003, 12(2): 97-99
作者姓名:陈丹梅  赵钢  唐建武  李连宏  丁建华  高泽红  朱英
作者单位:1. 大连理工大学医院,大连市,116023
2. 大连医科大学第一附属医院
3. 大连医科大学病理中心
4. 大连理工大学物理研究所
5. 大连大学医学院
6. 大连市第六人民医院
基金项目:辽宁省科技厅资助项目(990221430)
摘    要:目的 探讨用激光诱发自体荧光光谱(LIAF)技术对肝纤维化进行诊断的意义。方法 用SD大鼠100只,白蛋白、乙醇、四氯化碳和蛋白加贺普丁诱导造成肝纤维化模型。应用激光诱发自体荧光光谱检测正常大鼠血清与肝纤维化大鼠的血清。结果 肝纤维化大鼠血清的荧光平均主峰值出现了红移。结论 应用激光诱发自体荧光光谱技术,对肝纤维化大鼠的血清进行光谱分析,可找到一些有价值的数据,以用于肝纤维化的

关 键 词:激光 诱发 诊断 肝纤维化 LIAF技术
文章编号:1003-9430(2003)02-0097-03
收稿时间:2001-09-02
修稿时间:2001-09-02

Diagnosis of Rat Liver Fibrosis by Laser- induced Autofluorescence
CHEN Dan-mei ,ZHAO Gang ,TANG Jian-wu ,LI Lian-hong ,DING Jian-hua ,GAO Ze-hong ,ZHU Ying .Hospital,Dalian University of Technology,Dalian,China.Pathology Center,Dalian Medical University. Diagnosis of Rat Liver Fibrosis by Laser- induced Autofluorescence[J]. Chinese Journal of Laser Medicine & Surgery, 2003, 12(2): 97-99
Authors:CHEN Dan-mei   ZHAO Gang   TANG Jian-wu   LI Lian-hong   DING Jian-hua   GAO Ze-hong   ZHU Ying .Hospital  Dalian University of Technology  Dalian  China.Pathology Center  Dalian Medical University
Affiliation:CHEN Dan-mei 1,ZHAO Gang 2,TANG Jian-wu 3,LI Lian-hong 2,DING Jian-hua 4,GAO Ze-hong 5,ZHU Ying 6 1.Hospital,Dalian University of Technology,Dalian116023,China2.Pathology Center,Dalian Medical University 3.The First Hospital Attached to Dalian Medical University 4.Physics Institute,Dalian University of Technology 5.Medical College,Da lian University 6.The Sixth Hospita l of Dalian
Abstract:Objective To explore the significance of diagn osis of liver fibrosis by laser -induced autofluorescence(LIAF).Methods Liver fibrosis model of 100SD rats is induced by the different materials,namely,albumin,alcohol and CCl 4 .The serum of normal rat and rat with liver fibrosis is detected by LIAF.Results The spectra average peak of serum of r at with liver fibrosis takes place re d -movement.Conclusions Some worthy data can be found by detecting the serum of rat liver fibrosis b y LIAF,which is useful for diagnosin g the liver fibrosis,especially in early stage.
Keywords:Liver fibrosis  Diagnosis  Laser -i nduced autofluorescence
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