钬激光治疗阴囊Paget病的临床疗效观察

目的探讨钬激光治疗阴囊Paget病的疗效。方法 17例患者,年龄56~86岁,平均71岁,术前均行皮肤活检证实,分期为A期,进行钬激光治疗。结果手术时间20~60 min,术后均Ⅰ期愈合。3例术后局部复发,再次行钬激光治疗,术后随访1~2年未见复发。其余14例随访1~3年无复发。结论钬激光治疗可以成为治疗阴囊Paget病A期患者的主要方法。

Clinical research of holmium laser therapy of scrotum Paget disease

Objective To investigate the holmium laser therapy of scrotum Paget disease.Methods Seventeen patients with scrotal skin lesions confirmed as scrotum Paget disease in stage A by biopsy were carried out the treatment of holmium laser on the basis of the anti-infection and the skin preparation.All patients were followed up.The relapsing patients were cured by holmium Laser.Results The mean operation time was 20～60 minutes.The surgery was totally undertaken but only 3 case was done a second time because of postoperative recurrence.The fourteen patiens were not recurred during 1 to 3 years while the three patiens of second time were not recurred during 1 to 2 years.Conclusion The patients with scrotal skin lesions should be diagnosed by biopsy as early as possible and the holmium laser therapy might be the best means of curing the disease in stage A.