肺炎克雷伯菌医院感染及耐药性监测

目的调查医院肺炎克雷伯菌的耐药现状,为临床合理用药提供依据。方法用K-B法做体外药敏试验,用纸片确证法检测产超广谱β-内酰胺酶(ESBLs)细菌。结果我院肺炎克雷伯菌产ESBLs率为25.8%;128株肺炎克雷伯菌对亚胺培南100%敏感,对阿米卡星耐药率为10.9%,对其余6种常用抗菌药物耐药率均>40%。结论医院应重视肺炎克雷伯菌的耐药监测,以预防医院感染的发生与暴发流行。

Drug Resistance Status and Nosocomial Infections of Klebsiella pneumoniae in Our Hospital

OBJECTIVE To investigate drug resistance status of Klebsiella pneumoniae and offer scientific basis for reasonable usage of antibiotics. METHODS Drug resistance was analyzed by using K-B method.The(ESBLs) producing strains detected by disc confirmed test. RESULTS The frequency of(ESBLs)-producing K.pneumoniae isolates was 25.8% in our hospital.All of the 128 strains were susceptible to imipenem.And the resistant rates to ciprofloxacin and amikacin were about 10.9%,the resistant rate to other 6 antibiotics were all above 40%. CONCLUSIONS It is important to supervise drug resistance of clinical isolates in hospital and we should try our best to prevent nosocomial outbreak and surveillance.