| 多发性骨髓瘤病人血清游离轻链检测的临床意义 |
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| 引用本文： | 石晶,崔中光,汪洪毅. 多发性骨髓瘤病人血清游离轻链检测的临床意义[J]. 齐鲁医学杂志, 2011, 26(3): 192-194 |
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| 作者姓名： | 石晶 崔中光 汪洪毅 |
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| 作者单位： | 青岛大学医学院血液科,山东青岛,266021 |
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| 摘 要： | 目的 探讨血清游离轻链(sFLC)在多发性骨髓瘤(MM)病人诊断、疗效判断中的临床意义.方法 应用免疫散射比浊法,测定40例初诊MM病人,30例正常对照及30例IgG型MM病人化疗后不同疾病阶段的sFLC水平.结果 初诊MM病人的sFLC水平较正常对照明显异常(t=18.69、18.09,P<0.01).IgG型MM病...
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| 关 键 词： | 多发性骨髓瘤 免疫球蛋白轻链 散射测浊法和比浊法 |
DETECTION OF SERUM FREE LIGHT CHAIN AND ITS CLINICAL SIGNIFICANCE IN PATIENTS WITH MULTIPLE MYELO-MA |
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| SHI JING,CUI ZHONG-GUANG,WANG HONG-YI. DETECTION OF SERUM FREE LIGHT CHAIN AND ITS CLINICAL SIGNIFICANCE IN PATIENTS WITH MULTIPLE MYELO-MA[J]. Medical Journal of Qilu, 2011, 26(3): 192-194 |
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| Authors: | SHI JING CUI ZHONG-GUANG WANG HONG-YI |
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| Affiliation: | SHI JING,CUI ZHONG-GUANG,WANG HONG-YI(Qingdao University Medical College,Qindao 266021,China) |
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| Abstract: | Objective To assess the clinical significance of serum free light chain(sFLC) detection in the diagnosis and assessment of therapeutic efficacy of multiple myeloma(MM). Methods sFLC in 40 newly diagnosed patients,30 healthy people,and 30 type IgG MM at different post-chemotherapeutic stages were detected by immuno-nephelometric assays. ResultsThe difference of sFLC levels between MM patients and the normal control was significant(t=18.69,8.09;P<0.01).The sFLC level of 30 IgG MM patients declined gradually a... |
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| Keywords: | multiple myeloma immunoglobulin light chain nephelometry and turbidimetry |
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