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PF方案化疗同步放射治疗局部中晚期鼻咽癌的5年疗效分析
引用本文:曾睿芳,苏勇,邓雪英,夏云飞,吴峥.PF方案化疗同步放射治疗局部中晚期鼻咽癌的5年疗效分析[J].中华肿瘤防治杂志,2011,18(1):43-46.
作者姓名:曾睿芳  苏勇  邓雪英  夏云飞  吴峥
作者单位:1. 华南肿瘤学国家重点实验室,中山大学肿瘤防治中心放疗科,广东,广州,510060
2. 东莞市人民医院放疗科,广东,东莞,523000
摘    要:目的:探讨用PF方案同期化疗联合放射治疗局部中晚期鼻咽癌5年疗效.方法:52例局部中晚期鼻咽癌患者,在放疗第1、5周联合PF方案化疗,DDP70 mg/㎡,d1,静脉滴入;5-FU 500 mg/㎡,d2起96 h静脉灌注,共2个周期.另配对选取同时期52例单纯放疗者为时照组,两组放疗方法和剂量相似.结果:治疗结束后3...

关 键 词:鼻咽肿瘤/药物疗法  鼻咽肿瘤/放射疗法  综合疗法  顺铂/治疗应用  氟尿嘧啶/治疗应用

Five-year efficacy analysis of PF chemotherapy combined with radiotherapy in patients with local-advanced nasopharyngeal Carcinoma
ZENG Rui-fang,SU Yong,DENG Xue-ying,XIA Yun-fei,WU Zheng.Five-year efficacy analysis of PF chemotherapy combined with radiotherapy in patients with local-advanced nasopharyngeal Carcinoma[J].Chinese Journal of Cancer Prevention and Treatment,2011,18(1):43-46.
Authors:ZENG Rui-fang  SU Yong  DENG Xue-ying  XIA Yun-fei  WU Zheng
Institution:ZENG Rui-fang1,SU Yong1,DENG Xue-ying2,XIA Yun-fei1,WU Zheng11.State Key Laboratory of Oncology in South China,Department of Radiation Oncology,Cancer Center of Sun Yat-sen University,Guangzhong 510060,P.R.China2.Department of Radiation Oncology,People's Hospital of Dongguan,Dongguan 523000,P.R.China
Abstract:OBJECTIVE:This study was to investigate the 5-year efficacy of PF chemotherapy combined with radiotherapy in local-advanced nasopharyngeal carcinoma.METHODS: A total of 52 eligible patients with local-advanced NPC(CRT group) received two cycles of concurrent chemotherapy with cisplatin 70 mg/m2 intravenously on day 1 plus 5-fluorouracil 500 mg/m2 by 96-hour continuous infusion on day 2,during the weeks 1 and 5 of radiotherapy.Another 52 patients(RT group) matched with the CRT group were treated with radioth...
Keywords:nasopharyngeal neoplasms/drug therapy  nasopharyngeal neoplasms/radiotherapy  combined modality therapy  cisplatin/therapeutic use  fluorouracil/therapeutic use  
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