影响立体定向治疗颞叶癫痫预后的危险因素探讨

目的 探讨影响立体定向杏仁核、海马毁损术治疗颞叶癫痫预后的危险因素。方法 以立体定向杏仁核、海马毁损术治疗33例颞叶癫痫患者，经过1年的随访，以术后癫痫发作频率评分系统对疗效进行评分，分析婴儿期热性惊厥史、先兆术前抽搐发作频率、初发年龄、患病时间、手术年龄和疗效的关系。结果 有婴儿期热性惊厥史患者和无婴儿期热性惊厥史患者疗效比较差异有显著性，前者的疗效优于后者，而先兆、发作频率、初发年龄、患病时间和手术年龄两组之间差异无显著性。结论 婴儿期热性惊厥史是影响立体定向杏仁核、海马毁损术治疗颞叶癫痫预后的危险因素。

Risk factors predictive of outcome of stereotactic amygdalohippocampotomy for the treatment of temporal lobe epilepsy

Objective\ To investigate risk factors which predict the outcome of stereotactic amygdalohippocampotomy for the treatment of temporal lobe epilepsy. Methods\ The outcome of stereotactic amygdalohippocampotomy was assessed in 33 temporal lobe epilepsy patients.The history of febril seizure,aura,seizure frequency and age of onset of epilepsy,duration of epilepsy and age at surgery were compared with patients's outcomes. Results\ The mean age at surgery, duration of epilepsy, age of onset of epilepsy incidence of aura, and frequent seizures did not differ significantly between the two groups.But there was significant difference between patients with and without history of febril seizure. Conclusions\ The history of febril seizure is the risk factor which predicts outcome of stereotactic amygdalohippocampotomy for the treatment of temporal lobe epilepsy.