500例慢性肾小球肾炎患者少阳病流行病学调查

目的对慢性肾小球肾炎患者中少阳病的患病情况及少阳病可能相关因素进行调查，为和解少阳法治疗本病提供参考依据。方法采用流行病学现场调查的方法，对2007年10-11月收集的500例慢性肾小球肾炎患者的人口学、中医证候学及实验室检查资料，运用SPSS软件进行统计分析。结果两家医院500例患者中咽于、耳鸣耳聋、目眩、口苦、胸胁苦闷等少阳病常见症状出现频数均〉20％，少阳病患病率为19．8％；近期有外感者患病率为42．6％，无外感者为13．0％，二者差异有统计学意义（P〈0．01）。各证型的慢性肾小球肾炎患者少阳病的患病率差异有统计学意义（P〈0．01），脾肾气虚患者更易患病（患病率35．5％）。女性患病率更高（22．9％）．与男性少阳病患病率（11．7％）差异有统计学意义（P〈0．05）。不同肾功能状况、病程及年龄段的患者少阳病患病率差异无统计学意义（P〉0．05）。结论慢性肾小球肾炎患者少阳病患病率外感后较高；少阳病患病率与肾功能状况、病程及年龄未见明显相关性，脾肾气虚型患者及女性更易患病；和解少阳法可以参考用于慢性肾小球肾炎的辨证治疗。

Epidemiological survey on shaoyang disease in 500 patients with chronic glomerulonephritis

Objective To investigate the distribution pattern of shaoyang disease and TCM syndrome in patients with chronic glomerulonephritis（ CGN）, in an attempt to provide an evidence for the diagnosis and treatment of shaoyang disease in the patients with CG. Methods Epidemiological survey was adopted to collect the information of 500 CGN patients in 2 hospitals in Shanghai, including demography, TCM syndrome and laboratory findings. Futhermore, explore the distribution of pattern shaoyang disease and TCM syndrome of CGN patients, and analyze their relevant factors. Results 19.8% of the 500 CGN patients had been diagnosed with shaoyang disease, 42.6% of the patients who had got cold before the survey suffered from shaoyang disease, while 13.0% of the patients hadn＇ t got cold before the survey. Patients with different syndromes had different case rate of shaoyang disease ; the patients with syndrome of qi deficiency of spleen and kidney got shao yang disease more susceptibly than others. Fenmle patients seemed to be liable to shaoyang disease. Probability of over 20% could be found in the TCM syndromes as yin deficiency, qi deficiency, yang deficiency, damp-heat and blood stasis syndrome, the highest rale （59.4%） was found in yin deficiency of liver and kidney syndrome and the lowest（9.4% ） in yang deficiency of spleen and kidney. The distribution pattern of TCM syndrome has obvious dependability with the patients＇ age, while has no obvious dependability with duration of disease, sex or condition of renal function. Conclusion CGN patients are vulnerable to shaoyang disease, and the case rate is higher in patients after catching cold. The patients with syndrome of qi deficiency of spleen and kidney got shaoyang disease more susceptibly than others. Female patients seem to be liable to shaoyang disease.