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老年人P-选择素与肌钙蛋白T的相关性研究
引用本文:张江蓉,潘志红,袁惠敏,卢维晟,李东霞,王一尘. 老年人P-选择素与肌钙蛋白T的相关性研究[J]. 中国综合临床, 2008, 24(10)
作者姓名:张江蓉  潘志红  袁惠敏  卢维晟  李东霞  王一尘
作者单位:上海交通大学医学院附属新华医院老年科,上海,200092
摘    要:目的 观察老年人P-选择素和肌钙蛋白T的相关性.方法 80例老年患者分别同时检测P-选择素和肌钙蛋白T,根据肌钙蛋白T的高低将患者分为A组(肌钙蛋白正常组)和B组(肌钙蛋白异常组).分别比较两组P-选择素及与肌钙蛋白T的关系.结果 P-选择素B组明显增高,两组比较差异有统计学意义(P<0.01).单因素分析结果 表明P-选择素和肌钙蛋白T呈正相关(r=0.824,P<0.01).结论 P-选择素较肌钙蛋白T对心脏的敏感性和特异性低,但与肌钙蛋白T联合监测是间接判断冠状动脉病变及心肌损伤的程度和预后的简捷和方便的检测方法 .

关 键 词:P-选择素  肌钙蛋白T  老年人

Correlation between P-selectin and troponin-T in aged people
ZHANG Jiang-rong,PAN Zhi-hong,YUAN Hui-min,LU Wei-sheng,LI Dong-xia,WANG Yi-chen. Correlation between P-selectin and troponin-T in aged people[J]. Clinical Medicine of China, 2008, 24(10)
Authors:ZHANG Jiang-rong  PAN Zhi-hong  YUAN Hui-min  LU Wei-sheng  LI Dong-xia  WANG Yi-chen
Abstract:Objective To observe the correlation between P-selectin and troponin-T in aged people.Meth-ods P-selectin and troponin-T were detected in 80 patients,who were divided into two groups according to the level of troponin-T:group A(normal level of tropenin-T)and group B (abnormal level of troponin-T).The relationship of P-selectin and tropenin-T were compared in the two groups.Results P-selectin in group B was increased remark-ably than that in group A(P<0.01).P-selectin had positive correlation with tropenin-T by single factor analysis(r=0.824.P<0.01).Conclusion Cardiac sensitivity and specificity of P-selectin is lower than that of troponin-T,but both P-selectin and troponin-T offer simple and convenient methods of indirect judgment of the degree and prog-nosis of coronary artery disease and myocardial damage.
Keywords:P-selectin  troponin-T  Aged people
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