骨巨细胞瘤的影像学表现及其病理关系研究

【目的】探讨骨巨细胞瘤的影像学表现及其影像病理联系。【方法】分析31例骨巨细胞瘤的X线平片、CT、MRI与SPECT的影像特点及其病理组织学表现，并研究其影像病理的相关性。【结果】31例骨巨细胞瘤中，均没有伴发动脉瘤样骨囊肿，其余影像特征、病理组织学表现以及流行病学与文献报道相似：CT、MRI对软组织肿块、骨性分隔等侵袭性特征的显示明显优于普通X线平片，且以MRI为更好；病理分级上Ⅰ级3例，Ⅰ～Ⅱ级16例，Ⅱ级8例，Ⅱ～Ⅲ级4例。肿瘤的影像学表现尤其是CT、MRI在一定程度上能反映其组织学构成，但与病理分级无明显相关性。【结论】骨巨细胞瘤的影像学表现与其病理分级无相关性，CT和MRI能改善对软组织蔓延等侵袭性特征的评价并指导制定治疗方案。

The imaging appearances of giant cell tumors of The bone: radiologic-pathologic correlation

Objective] To analysis the imaging appearances of giant cell tumors of the bone and radiologic - pathologic correlation. Methods] The appearances of x-ray plain film, CT, MRI and SPECT and pathology were evaluated in 31 cases, as well as the correlation between them. Results] The imaging characteristics, pathology and epidermology were similar to the results in the literature except without aneurysmal bone cyst followed. CT and MRIwere better than X-ray plain film on demonstrating the invading appearances such as soft tissue masses, bone septations and so on, especially MRI. There were 3 cases of the Ⅰ grade, 16 cases of the Ⅰ-Ⅱ grade, 8 cases of the Ⅱ grade, 4 cases of the Ⅱ-Ⅲ grade of the giant cell tumors. The imaging manifestations, especially CT and MRI, of the tumors reflected the components of pathology in an extent, however, there was no significant correlation between the imaging appearances and pathologic grades. Conclusions] Although without correlation between the the imaging characteristics and the grades of the tumors, CT and MRIcan improve the evaluation of the invading manifestations, which may direct the therapeutic protocal.