Isolation and characterization of an antimalarial agent of the neem tree Azadirachta indica |
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Authors: | S A Khalid H Duddeck M Gonzalez-Sierra |
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Affiliation: | Department of Pharmacognosy, Faculty of Pharmacy, University of Khartoum, Sudan. |
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Abstract: | The isolation and structure elucidation of gedunin [1], the antimalarial agent of Azadirachta indica, are reported. Its 1H- and 13C-nmr spectra were assigned by using one- and two-dimensional nmr spectroscopy, especially homonuclear and heteronuclear COSY, nOe difference, and COLOC experiments. |
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