| 二甲双胍对糖耐量减低者同型半胱氨酸的影响研究 |
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| 引用本文： | 李改仙,苏胜偶. 二甲双胍对糖耐量减低者同型半胱氨酸的影响研究[J]. 成都医学院学报, 2008, 3(4): 280-282 |
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| 作者姓名： | 李改仙 苏胜偶 |
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| 作者单位： | 华北石油总医院,河北任丘,062552;河北医科大学第二医院内分泌科,石家庄,050000 |
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| 摘 要： | 通过检测二甲双胍治疗糖耐量减低（IGT）患者血浆同型半胱氨酸、维生素B6、维生素B12、叶酸水平变化情况，探讨二甲双胍对IGT患者血浆同型半胱氨酸水平的影响，结果血浆总同型半胱氨酸水平与BMI、WL、FBG、PBG、DBP、TG等指标相关，经短期二甲双胍治疗IGT患者血浆维生素B6、维生素B12逐渐下降，叶酸不受影响，而逐渐上升，血浆总同型半胱氨酸上升。
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| 关 键 词： | 二甲双胍 糖耐量减低 同型半胱氨酸 维生素B6 维生素B12 叶酸 |
The Study on Effect of the Plasma Homocysteine in Metformin Treated Impaired Glucose Tolerance |
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| LI Gai-xian,SU Shen-gou. The Study on Effect of the Plasma Homocysteine in Metformin Treated Impaired Glucose Tolerance[J]. Journal of Chengdu Medical College, 2008, 3(4): 280-282 |
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| Authors: | LI Gai-xian SU Shen-gou |
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| Affiliation: | LI Gai-xian, SU Sheng-ou( 1. General Hospital of Huabei Oil Adrministration Bureau, hebei Renqiu, 062552 ; 2. Department of Endocrinology, The Second Affiliated Hospital of Hebei Medical University, Shijiazhuang 050000, China) |
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| Abstract: | This research now give an observation study and pass examination metformin treated in impaired glucose toleranc （IGT） sufferer＇s blood plasma homocyseine, vitamin B6, vitamin B12, folic acid level variety circumstance, to study the effect of metformin on the IGT sufferer＇s blood plasma homocysteine level. The blood plas ma homocysteine level related to BMI, WL, FBG, PBG, DBP, TG, etc. Through short term treatment of metformin in IGT, plasma vitamin
B6, the vitamin B12 gradually descended, the folic acid was uninfluenced, blood ptasma total homocysteine climed. |
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| Keywords: | metformin impaired glucose tolerance homocystein Vitamin B6 Vitamin B12 folic acid |
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