中医预防颈动脉粥样硬化危险因素研究进展

目的：探究中医防治颈动脉粥样硬化危险因素研究情况,研究各种危险因素与颈动脉粥样硬化之间的关系,并探讨预防策略。方法：2009年5月～2010年6月我院选取50例采用中医进行预防性治疗的颈动脉粥样硬化患者,同时选取50例采用西医治疗的颈动脉粥样硬化患者,回顾分析其临床资料,对比分析两组患者的颈动脉粥样硬化危险因素血清C-反应蛋白（CRP）及血液中白细胞（WBC）,同时检测两组患者的血脂和空腹血糖。结果：中医组的CRP,WBC,血脂及血糖水平均低于西医治疗组,其中CRP,WBC水平比较尤其显著,两组患者之间比较差异具有统计学意义（P〈0.05）。对中医治疗组CRP,WBC,血脂及血糖水平指标进行单因素分析时,CRP,WBC分别与患者的TC、TG、LDL及空腹血糖指标成正相关（P〈0.05）,而与HDL水平呈现负相关（P〈0.05）。结论：采用中医预防性治疗患者颈动脉粥样硬化危险因素的发生以及体内血脂、血糖的异常代谢的临床效果良好,可以进一步进行临床研究。

A review on preventing risk factors of carotid atherosclerosis in TCM

Objective:To explore risk factors of carotid atherosclerosis,research various risk factors and carotid atherosclerosis. Methods:May 2009-May 2010-June 50 patients treated for preventive therapy in TCM,and other 50 cases were treated with Western medicine treatment,and recorded data,serum C-reactive protein(CRP)and blood leukocytes(WBC),lipids and fasting glucose.Results: CRP,WBC,blood lipids and glucose levels were lower than the Western medicine treated group,difference between the two groups were statistically significant(P<0.05).TCM group CRP,WBC,blood lipids and glucose level indicators respectively and the patient’s TC,TG, LDL,and fasting blood sugar level was positively correlated(P<0.05),but with HDL levels are negatively related(P<0.05)Conclusion: The preventive treatment of TCM for the occurrence of risk factors in body lipids,blood glucose abnormal metabolism can receive good clinical results,and need further clinical studies.