| 艾亚林对牙周炎患者龈沟液中IL-1的影响 |
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| 引用本文： | 谭葆春,杨明华,钱海峰,肖健平,吴文蕾,林楠. 艾亚林对牙周炎患者龈沟液中IL-1的影响[J]. 口腔医学研究, 2006, 22(5): 498-500 |
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| 作者姓名： | 谭葆春 杨明华 钱海峰 肖健平 吴文蕾 林楠 |
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| 作者单位： | 南京市口腔医院牙周科,江苏,南京,210008;南京市口腔医院牙周科,江苏,南京,210008;南京市口腔医院牙周科,江苏,南京,210008;南京市口腔医院牙周科,江苏,南京,210008;南京市口腔医院牙周科,江苏,南京,210008;南京市口腔医院牙周科,江苏,南京,210008 |
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| 摘 要： | 目的:研究艾亚林(盐酸米诺环素牙用缓释膜)对牙周炎患者龈沟液中IL-1和临床症状的影响。方法:选择门诊病人中、重度慢性牙周炎患者30例,分别于使用艾亚林前后检测牙周探诊深度、附着丧失、探诊出血、记录松动度、牙龈指数,龈沟液量及IL-1浓度。结果:除附着丧失和松动度外,其他指标在用药前后均有显著性差异。结论:艾亚林可明显减轻牙周炎患者的临床症状,有效抑制炎症介质IL-1的产生。
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| 关 键 词： | 牙周炎 盐酸米诺环素 IL-1 |
| 文章编号： | 1671-7651(2006)05-0498-03 |
| 修稿时间： | 2006-04-05 |
Influence of Aiyalin to IL-1 in Gingival Crevicular Fluid of Periodontitis Patients |
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| TAN Bao-chun,YANG Ming-hua,QIAN Hai-feng,et al.. Influence of Aiyalin to IL-1 in Gingival Crevicular Fluid of Periodontitis Patients[J]. Journal of Oral Science Research, 2006, 22(5): 498-500 |
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| Authors: | TAN Bao-chun YANG Ming-hua QIAN Hai-feng et al. |
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| Affiliation: | TAN Bao-chun,YANG Ming-hua,QIAN Hai-feng,et al.Department of Periodontal Disease,the Stomatology Hospital of Medical College of Nanjing University,Nanjing 210008 |
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| Abstract: | Objective: To study the influence of aiyalin(Minocycline HCL dental S.R.Pellicle) to IL-1 in gingival crevicular fluid and to clinical symptoms of periodontal patients.Methods: We choose medium to serious periodontitis patients,then test probing depth,attachment loss,bleeding on probing,gingival index,loosen degree,quantity of gingival crevicular fluid and IL-1 before and after using aiyalin.Results: The difference of all indices before and after using aiyalin are statistically significant except attachment loss and loosen degree.Conclusion: Aiyalin can reduce the clinical symptoms of periodontal and inhibit the production of IL-1. |
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| Keywords: | Periodontitis Minocycline HCL IL-1 |
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