A search for calcium-channel activators in the verapamil series |
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Authors: | M N Romanelli F Gualtieri R Mannhold A Chiarini |
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Affiliation: | Dipartimento di Scienze Farmaceutiche, Università di Firenze, Italy. |
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Abstract: | A new series of phenylalkylamines related to Verapamil have been synthesized and their Ca2+-modulating activity on rabbit aorta and on guinea-pig heart were evaluated. The compounds display only a moderate Ca2+-antagonistic activity; none of them showed any Ca2+-agonistic effect. |
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