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Rare localization of extrarenal nephroblastoma in 1-month-old female infant
Authors:Armanda Višnja  Culić Srđana  Pogorelić Zenon  Kuljiš Dubravka  Budimir Dražen  Kuzmić-Prusac Ivana
Institution:1. Split University Hospital Center, Department of Pediatric Hematology, Oncology, Immunology and Medical Genetics, Medical School University of Split, Spin?i?eva 1, 21000 Split, Croatia;2. Split University Hospital Center, Department of Pediatric Surgery, Medical School University of Split, Spin?i?eva 1, 21000 Split, Croatia;3. Split University Hospital Center, Department of Pathology, Forensic Medicine and Cytology, Medical School University of Split, Spin?i?eva 1, 21000 Split, Croatia;1. Department of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, White 502, 55 Fruit Street, Boston, MA 02114, USA;2. Department of Surgery, Division of Neurosurgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA;3. Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA;1. Department of Neurosurgery, University Medicine of Rostock, Rostock, Germany;2. Institute for Pathology, University Medicine of Rostock, Rostock, Germany;3. Institute for Biostatistics and Informatics in Medicine, University Medicine of Rostock, Rostock, Germany;4. Department of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany;5. Institute for Diagnostic and Interventional Radiology, University Medicine of Rostock, Rostock, Germany;1. Neurosurgery Division, Department of Clinical Neurosciences, Faculty of Medicine, Geneva University Medical Center, Geneva, Switzerland;2. Department of Spine Surgery and Neurosurgery, University of Fribourg, Hôpital Fribourgeois, Chemin des Pensionnats 2-6, 1700 Fribourg, Switzerland;3. Interventional Neuroradiology Division, Department of Radiology and Medical Informatics, Faculty of Medicine, Geneva University Medical Center, Geneva, Switzerland;4. Department of Neuroradiology, University Hospital of Zurich, Frauenklinikstraße 10, 8091 Zürich, Switzerland;1. Department of Neurosurgery, Medical Faculty, Otto-von-Guericke University Magdeburg, Magdeburg, Germany;2. Department of Neurology, Medical Faculty, Otto-von-Guericke University Magdeburg, Magdeburg, Germany;3. StatConsult, Gesellschaft für klinische und Versorgungsforschung mbH, Magdeburg, Germany;4. Institute for Biometry and Medical Informatics, Medical Faculty, Otto-von-Guericke University Magdeburg, Magdeburg, Germany
Abstract:Extrarenal occurrence of Wilms' tumor is exceptional and the diagnosis is almost always made after surgery. The exact mechanism whereby a Wilms' tumor occurs in extrarenal tissue is unknown. The tumor is most commonly located in the retroperitoneum or inguinal region. Localization in subcutaneous tissue is extremely rare. In this paper, the case of a 1-month-old female infant with an extrarenal Wilms' tumor located in the lumbosacral region is presented. Surgical excision is the treatment of choice, and the same general therapeutic rules should be followed as when the kidney is affected.
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