Neonatal myasthenia gravis : Anti-acetylcholine receptor antibodies in the amniotic fluid |
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| Authors: | Evelyne Morel, Jean-Fran ois Bach, Marie-Louise Briard,Jean-Pierre Aubry |
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| Affiliation: | 1. INSERM U25 and CNRS LA 122 and Clinique de Génétique Médicale, Hôpital Necker - Enfants Malades, 161 rue de Sèvres, 75730 Paris Cédex 15, France;2. Maternité Port-Royal, 121 boulevard de Port Royal, 75014 Paris, France |
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| Abstract: | Neonatal myasthenia gravis (NMG) with mild arthrogryposis was observed at birth in the newborn infant of a myasthenic mother. Anti-acetylcholine receptor (anti-AChR) antibodies were present in the serum of both mother and child, in umbilical cord serum and in the amniotic fluid. The presence of anti-AChR antibodies in the amniotic fluid may be one of the causes of the NMG. |
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| Keywords: | Amniotic fluid Anti-acetylcholine receptor antibodies Arthrogryposis Neonatal myasthenia gravis |
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