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Loss of an IgG plasma cell checkpoint in patients with lupus
Authors:Jolien Suurmond  Yemil Atisha-Fregoso  Emiliano Marasco  Ashley N Barlev  Naveed Ahmed  Silvia A Calderon  Mei Yin Wong  Meggan C Mackay  Cynthia Aranow  Betty Diamond
Institution:1. Center of Autoimmune Musculoskeletal and Hematopoietic Diseases, Feinstein Institute for Medical Research, Northwell Health, Manhasset, NY;2. Tecnologico de Monterrey, Monterrey, Mexico;3. Division of Rheumatology, Ospedale Pediatrico Bambino Gesù IRCCS, Rome, Italy;4. Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Manhasset, NY;5. College of Osteopathic Medicine, New York Institute of Technology, Old Westbury, NY;6. School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom
Abstract:
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  • Keywords:Plasma cells  tolerance  autoimmunity  systemic lupus erythematosus  ANA  Antinuclear antibodies  BCR  B-cell receptor  BM  Bone marrow  dsDNA  Double-stranded DNA  SLE  Systemic lupus erythematosus
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