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The pharmacokinetics of morphine and its glucuronide conjugate in a rat model of streptozotocin‐induced diabetes and the expression of MRP2, MRP3 and UGT2B1 in the liver |
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| Authors: | Yoshitaka Hasegawa Shuichi Kishimoto Naoki Shibatani Hiromichi Nomura Yuko Ishii Mika Onishi Nobuo Inotsume Yoshikazu Takeuchi Shoji Fukushima |
| Institution: | 1. Laboratory of Clinical Pharmaceutics, Faculty of Pharmaceutical Sciences, Kobe, Japan;2. Cooperative Research Center of Life Science, Kobe Gakuin University, Kobe, Japan;3. Division of Clinical Pharmaceutics, Hokkaido Pharmaceutical University School of Pharmacy, Otaru, Japan |
| Abstract: | |
| Keywords: | diabetes morphine morphine‐3‐glucuronide pharmacokinetics transporter |