亚健康状态人群的脉象图特征分析

目的：研究不同健康状态及亚健康各证型的脉象图参数,探求评价亚健康状态的特征性脉象图指标。方法：运用＂健康状态评价问卷H20.V2009＂对1275例无明确急慢性疾病者进行健康状态评估,并分为健康组和亚健康组,依据＂亚健康状态辨证依据V2010＂,对亚健康者进行辨证分型。另设明确诊断的患有心血管疾病的患者121例作为对照。用YJJ-101亚健康脉象监测系统采集脉象,分析主波幅度（amplitude of main wave,h1）,重搏波前波幅度（amplitude of front wave,h3）,重搏波幅度（amplitude of repeat wave,h5）,主波上1/3处宽度（1/3width of main wave,w1）,主波上1/5处宽度（1/5width of main wave,w2）,左心室快速射血期时值（time of rapid ejection phase,t1）,脉动周期（period of pulse,t）,脉象图总面积（square of pulse diagram,S）、收缩期面积（area in systole,As）、舒张期面积（area in diastole,Ad）,采脉压力（pulse pressure,Pp）和h3/h1、h5/h1、w1/t、w2/t、h1/t1比值等。结果：健康组、亚健康组与疾病组3组比较：与健康组相比,亚健康组w1/t、w2/t增高,Pp、h1、h5、h5/h1、S、As、Ad降低;与疾病组相比,亚健康组Pp、h5/h1增高,h1、w2/t、S、As降低。健康组、实证组与虚证组3组比较：与健康组相比,实证组与虚证组均表现为h3/h1、w1、w1/t、w2/t增高,h1、h5、h1/t1、h5/h1降低。健康组与各证候组比较：各证候组间比较,脉象图参数h1、h5在肝郁组、阴虚组、气虚组、实热组依次降低,脉象图参数h3/h1、w1/t在肝郁组、实热组、阴虚组、气虚组依次升高,肾虚组脉象图指标h1显著高于健康组及其他证候组。结论：不同健康状态、亚健康不同类别及各证型的脉象图参数存在较明显差异,脉象图特征指标可作为客观评价不同健康状态、亚健康分类量化诊断、辨证分型研究的实验依据之一。

Analysis on pulse diagram characteristics of subjects with subhealth state

To study the pulse diagram parameters of subjects with subhealth state and to find the pulse parameters for subhealth state evaluation. METHODS： A total of 1 275 subjects without diagnosed diseases were recruited and their health conditions were assessed with Health Evaluating Questionnaire H20 V2009. The subjects were assigned to health group or subhealth group according to the scale score. Subjects＇ syndrome in the subhealth group was differentiated using score of ＂subhealth state of syndrome differentiation V2010＂. Another 121 patients with cardiovascular diseases were enrolled as a control. The pulse information was collected with Y J J-101 subhealth pulse monitoring system and the parameters include amplitude of main wave （h1）, amplitude of repeat wave （h5） and its front wave （h3）, 1/3 or 1/5 width of main wave （w1） or （w2）, time of rapid ejection phase （t2）, period of pulse （t）, pulse pressure （Pp）, square （S）, area in systole （As） and area in diastole （Ad） of pulse diagram and ratios of h3/h1, h5/h1, w1/t, w2/t and h1/t1. RESULTS： Pulse diagram analysis showed significant differences among health, subhealth and disease group in Pp, hi, S and As and ratios of h5/h1 and w2/t. Compared with the health group, the values of w1/t and w2/t of the subhealth group increased （P〈0.05）, and Pp, h1, h5, h5/h1, S, As and Ad decreased （P〈 0.05）. Compared with health group, the parameters of pulse of the subhealth group were increased in Pp and hS/hl （P〈0.05） and decreased in h1, w2/t, S and As （P〈0.05）. Compared with health group, pulse parameters h3/h,, w1, w1/t, w2/t of excess and deficiency syndrome group increased, and h1, h5, h1/t1 and h5/h1 decreased. Among different syndromes of h5/h1 and w1/t of yin deficiency, qi deficiency, subhealth state, pulse diagram parameters h1, h5, h3/h1, liver stagnation and excess heat group were significantly different （P〈0. 05） from the health group, for example, pulse parameters h1 and h5 of stagnation, yin deficiency, qi deficiency and excess heat group declined in order, and pulse parameters h3/h1 and w1/t of liver stagnation, excess heat, yin deficiency and qi deficiency group increased in order. Pulse index h1 in the kidney deficiency group was higher than that in the health group and the other syndrome groups. CONCLUSION： Results of analyzing sphygmogram parameters showed different characteristics among different health status and the subhealth state due to different syndromes. Sphygmogram parameters may be used for objective evaluation of health status or subhealth syndrome differentiation.