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Twist基因与乳腺癌关系的研究进展
引用本文:伏铠文,肖秀丽. Twist基因与乳腺癌关系的研究进展[J]. 川北医学院学报, 2014, 29(6): 640-644
作者姓名:伏铠文  肖秀丽
作者单位:泸州医学院附属医院病理科,四川泸州,646000
基金项目:泸州市科技局项目2012-S-36
摘    要:乳腺癌的发生和发展是一个多种基因参与调节的复杂过程,近年来研究发现Twist过表达在乳腺癌的发生、侵袭转移、血管生成与肿瘤细胞耐药中发挥重要作用,且其在乳腺癌中的表达对早期诊断和临床个体化治疗有重要意义。

关 键 词:乳腺癌  Twist  侵袭转移

Research progress of Twist gene in breast cancer
FU Kai-wen,XIAO Xiu-li. Research progress of Twist gene in breast cancer[J]. Journal of North Sichuan Medical College, 2014, 29(6): 640-644
Authors:FU Kai-wen  XIAO Xiu-li
Affiliation:(Department of Pathology ,Affiliated Hospital of Luzhou Medical College, Luzhou 646000, Sichuan , China )
Abstract:There are multiple genes involved in the progress of evolution in breast cancer. Recent studies have found that Twist overexpression is able to play a key role in tumorigenesis,invasion,metastasis,angiogenesis and drug resistance. Other studies also demonstrated that Twist gene expression may be related to early diagnosis and clinical individual therapy.
Keywords:Breast cancer  Twist gene  Invasion and metastasis
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