| Trauma-induced auditory nerve degeneration due to cerebellopontine（CP） angle manipulations： clinical and experimental experience |
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| 引用本文： | TetsujiSekiya. Trauma-induced auditory nerve degeneration due to cerebellopontine（CP） angle manipulations： clinical and experimental experience[J]. 中华神经医学杂志, 2004, 3(1): 5-10 |
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| 作者姓名： | TetsujiSekiya |
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| 作者单位： | Department of |
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| 摘 要： | In order to investigate the pathophysiologic mechanisms responsible for trauma-induced hearing disturbances due to auditory nerve degeneration, we established for the first time a rat experimental model in which auditory nerve degeneration due to compression injury of the cerebellopontine (CP) angle portion of the auditory nerve can be quantitatively evaluated. In this paper, I demonstrate our clinical experience in CP angle surgery and some of the results of our experiments performed on this rat experimental model. Trauma-induced hearing loss in CP angle operations has long been regarded as a sort of unavoidable "natural course" and therefore hopeless. I believe that this pessimistic view should be challenged and changed through new approaches in scientific research.
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| 关 键 词： | 听觉神经 外伤 手术 临床资料 |
Trauma-induced auditory nerve degeneration due to cerebellopontine(CP) angle manipulations:clinical and experimental experience |
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| Tetsuji Sekiya. Trauma-induced auditory nerve degeneration due to cerebellopontine(CP) angle manipulations:clinical and experimental experience[J]. Chinese Journal of Neuromedicine, 2004, 3(1): 5-10 |
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| Authors: | Tetsuji Sekiya |
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| Abstract: | In order to investigate the pathophysiologic mechanisms responsible for trauma-induced hearing disturbances due to auditory nerve degeneration, we established for the first time a rat experimental model in which auditory nerve degeneration due to compression injury of the cerebellopontine (CP) angle portion of the auditory nerve can be quantitatively evaluated. In this paper, I demonstrate our clinical experience in CP angle surgery and some of the results of our experiments performed on this rat experimental model. Trauma-induced hearing loss in CP angle operations has long been regarded as a sort of unavoidable "natural course" and therefore hopeless. I believe that this pessimistic view should be challenged and changed through new approaches in scientific research. |
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| Keywords: | auditory nerve cerebellopontine angle |
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