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维持性血液透析患者勃起功能障碍的初步研究
引用本文:师延斌,韩大正,赵志军,王孝兰.维持性血液透析患者勃起功能障碍的初步研究[J].中华肾脏病杂志,2002,18(5):361-363.
作者姓名:师延斌  韩大正  赵志军  王孝兰
作者单位:1. 475001,开封,河南大学第一附属医院血液净化中心
2. 475001,开封,河南大学第一附属医院内科
3. 475001,开封,河南大学第一附属医院彩色超声波室
摘    要:目的 明确维持性血液透析(MHD)男性患者勃起障碍的发病率,及评价西地那非的疗效与副作用。方法 以国际勃起功能指数(IIEF)对22例HD男患者进行评分。勃起障碍者给予西地那非,每次从25mg/d开始,最高为100mg/d,治疗12周,对比治疗前后IIEF分值变化。结果 MHD勃起障碍发病率为72.73%。西地那非总有效率为87.5%。常见的副作用为头痛,面色潮红等。结论 西地那非对于正在接近血液透析治疗的肾衰患者安全性和有效性等同于其它人群。

关 键 词:血液透析  西地那非  勃起功能障碍  肾功能衰竭  治疗

Preliminary research for erectile dysfunction in hemodialysis patients
SHI Yanbin,HAN Dazheng,ZHAO Zhijun,et al..Preliminary research for erectile dysfunction in hemodialysis patients[J].Chinese Journal of Nephrology,2002,18(5):361-363.
Authors:SHI Yanbin  HAN Dazheng  ZHAO Zhijun  
Institution:SHI Yanbin,HAN Dazheng,ZHAO Zhijun,et al. Department of Nephrology,The First Affiliated Hospital,Henan University,Kaifeng 475001,China
Abstract:Objective To estimate the prevalence of erectile dysfunction (ED) among the patients undergoing manintenance hemodialysis (MHD), and evaluate the efficacy and the adverse effects of sildenafil for ED. Methods The international index of erectile function questionnaire (IIEF) was used to estimate 22 male MHD cases. ED patients were administered sildenafil with the initial dose of 25 mg/d, then maximum of 100 mg/d for 12 weeks. Results 72. 73% (16/22) of MHD patients complained of ED, and the total effective rate of sildenafil was 87.5% (14/16) with common adverse effects-headache and flushing. Conclusion Sildenafil in MHD patients has similar efficacy and safety as the others.
Keywords:Hemodialysis  Sildenafil  Erectile dysfunction
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