持续静脉泵入硝酸甘油联合多巴酚丁胺治疗顽固性心力衰竭的临床观察

目的 观察硝酸甘油联合多巴酚丁胺治疗顽固性心力衰竭的疗效.方法 对90例Ⅲ～Ⅳ级顽固性心力衰竭患者,在采用常规综合治疗2～3 d无效的基础上,给予微量注射泵持续静脉泵注治疗量的硝酸甘油和多巴酚丁胺,疗程5～7d,观察患者临床症状、体征、心功能改善情况.结果 用药后,患者临床症状、体征、心功能明显改善,总有效率为95.5%.其中显效73例（81.1%）,有效13例（14.4%）,无效4例（4.5%）,疗效确切,不良反应无增加.结论 持续静脉泵入治疗量的硝酸甘油、多巴酚丁胺治疗顽固性心力衰竭有较好的临床效果.

Clinical observaion on the effect of refractory heart failure treated with nitroglycerin and dobutamine by continue venous pump

Objective To observe the effect of using nitroglycerin and dobutamine through continue venous pump for refractory heart failure. Methods Ninety patients with 3 -4 rank heart function were selected who were treated invalidly for 2 - 3 days by conventional therapy. Based on above treatment, these patients were treated with nitroglycerin and dobutamine by continue venous pump ,for 5 to 7 days. Clinical symptoms, signs and heart function were observed. Results The clinical symptoms, signs and heart function were improved obviously after using nitroglycerin and dobutamine by continue venous pump. The total effective rate reached 95.5%. Of them marked effect were found in 73 patients（81.1% ）,effective in 13 patients （14.4%）,invalid 4 patients （4. 5% ）. There were positive curative effects and not more adverse reactions. Conclusion The way of using nitroglycerin and dobutamine by continue venous pump can play a role in treating refractory heart failure.