局部注射重组人白介素-2预防尖锐湿疣复发临床疗效观察

目的 观察重组人白介素-2局部注射治疗预防尖锐湿疣复发的效果。方法治疗采用随机分组法，对照组消除疣体后局部外涂重组人于扰素α-2b乳膏治疗，3次／d，连续3个月；治疗组在此基础上每周加用100万u重组人白介素-2局部注射治疗，连续10周，于治疗后3、6个月观察对比两组尖锐湿疣复发率。结果治疗后3、6个月两组的复发率对比差异均有统计学意义（P〈0．05），治疗组低于对照组。结论重组人白介素-2局部注射治疗可降低尖锐湿疣复发率。

Clinical observation on local injection of recombinant human interleukin-2 in the prevention of recurrence of condyloma acnminatum

Objective To observe the clinical efficacy of recombinant human interleukin-2 in the prevention of recurrence of condyloma acuminatum. Methods The patients were divided into the treatment group and the control group randomly. All the patients treated with CO2 laser and local recombinant human interferon α-2b cream,three times a day for 3 months. The patients of the treatment group were additionally injected locally with the reeombinant human interleukin-2, 1 million u per week for 10 weeks. The relapse rates of two groups were observed at 3,6 months after treatment. Results The recurrence rate of the two groups had statistically significant differences （ P 〈 0. 05）. The recurrence rate of treatment group was lower than that of the eontrol group. Conclusion Local injection of reeombinant human interleukin-2 ean reduce the recurrence rate of eondyloma aeuminatum.