生脉注射液治疗慢性肺心病急性发作的疗效观察

目的 观察生脉注射液治疗慢性肺源性心脏病（肺心病）急性发作期的临床疗效。方法患者100例按随机原则分为生脉治疗组和对照组各50例，两组均予西医常规治疗，治疗组在常规治疗的基础上加用生脉注射液（生脉60ml加入5％葡萄糖注射液200ml中静脉滴注，1次／d），两组疗程均为14d。结果生脉组的PaO2上升及PaCO2下降水平较对照组显著（P均〈0．01），两组总有效率分别为92％和68％，治疗组高于对照组（P〈0．01）。生脉治疗组50例中除2例发生口干外，余无明显不良反应。结论采用生脉注射液治疗肺心病急性加重期，疗效显著，不良反应少，值得临床进一步研究推广。

Observation on therapeutic effect of Shengmai injection in the adjuvant treatment of patients with acute exacerbation of chronic pulmonary heart disease

Objective To observe the clinical therapeutic effect of Shengmai injection in the adjuvant treatment of patients with acute exacerbation of chronic pulmonary heart disease. Methods One hundred patients with acute exacerbation of chronic pulmonary heart disease were randomly divided into the Shengmai group （50 patients） and the control group （50 patients）. The patients in two groups were treated with conventional western medicine treatment. On the basis of above treatment, the patients in the Shengmai group were given intravenous drip of Shengmai injection 60 ml added into 5% glucose injection,once daily. The treatment course was 14 days. Results Increasing of PaO2 level and decreasing of PcO2 level in the Shengmai group were more remarkable than those in the control group （ all P 〈 0. 01 ）. Total effective rate in the Shengmai group （92%） was higher than that in the control group （68%） （ P 〈0. 01 ）. Except xerostomia which occured in 2 patients, there was no obvious adverse reaction in the Shengmai group. Condusion Shengmai injection in the adjuvant treatment of patients with acute exacerbation of chronic pulmonary heart disease has obvious therapeutic effect and less adverse reaction. It is worthy of further application.