消旋卡多曲与西咪替丁联用治疗小儿轮状病毒肠炎的疗效观察

目的 观察消旋卡多曲与西咪替丁联用治疗婴幼儿轮状病毒性肠炎的疗效。方法将112例符合条件的轮状病毒性肠炎的患儿随机分为两组，每组56例。两组常规补液纠正脱水和酸中毒，对症支持治疗等。在此基础上，观察组加消旋卡多曲与西咪替丁；对照组加服八面蒙脱石散。观察两组疗效。结果观察组与对照组的总有效率分别为94．6％和80．4％，两组总有效率差异有统计学意义（P〈0．05），观察组明显优于对照组。两组不良反应发生率分别为5．3％和1．7％。结论消旋卡多曲联合西咪替丁治疗婴幼儿轮状病毒性肠炎疗效显著、安全。

Observation of the effect of racecadotril combined with cimitidine in the treatment of children with rotaviral enteritis

Objective To observe the effect of racecadotril combined with cimitidine in the treatment of infants with rotaviral enteritis. Methods One hundred and twelve infants with rotaviral enteritis were randomly divided into two groups ,each 56. Conventional treatment included infusion to correct dehydration and acidosis, the treatment of symptoms and supportive management. On this basis, observation group took racecadotril and cimetidine and control group direct montmorillonite powder. Results The total effective rates of observation group and control group were 94. 6% and 80.4% respectively, the difference of the therapeutic effect between the two groups was significantl（P 〈 0.05）. The observation group was better than control group. The adverse reaction rates in the obserradon group and control group were 5. 3% and 1.7% respectively. Conclusion The therapy of racecadotril combined with cimitidine was effective and safe for the treatment of infants rotaviral enteritis.