Osteopontin as a potential biomarker of proliferation and invasiveness for lung cancer |
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| Authors: | Bai Zhao Tiemin Sun Fanjuan Meng Aibing Qu Chunling Li Hui Shen Yu Jin Wenxin Li |
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| Institution: | (1) Department of Urology Surgery, The Second Affiliated Hospital of Harbin Medical University, 150081 Harbin, China;(2) Department of Biotherapy, Tumor Hospital of Liaoning Province, 44 Xiaoheyan Road, Dadong District, 110042 Shenyang, Liaoning Province, China; |
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| Abstract: | Purpose Lung cancer is one of the most malignant tumors and poses a significant threat to human health. Osteopontin (OPN) is a variably
expressed, secreted glycophosphoprotein that mediates the growth and metastases of several carcinoma types. In this study,
we aimed to understand the role of OPN in lung cancer cell proliferation and invasiveness. |
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