| 免疫酶法检测鼻咽癌病人血清IgA/gp125抗体 |
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| 引用本文： | 薛绍礼 皮国华. 免疫酶法检测鼻咽癌病人血清IgA/gp125抗体[J]. 临床检验杂志, 1998, 16(5): 277-279 |
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| 作者姓名： | 薛绍礼 皮国华 |
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| 作者单位： | [1]安徽省医科大学分子生物学研究室 [2]中国预防医学科学院病毒学研究所 |
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| 摘 要： | 建立了用表达Ｅｐｓｔｅｉｎ－Ｂａｒｒ病毒壳抗原ｇｐ１２５的重组痘苗病毒感染细胞为抗原，检测ＩｇＡ／ｇｐ１２５抗体的免疫酶法，并检测了鼻咽癌病人血清其它肿瘤病人和正常人的ＩｇＡ／ｇｐ１２５抗体，其灵敏度远远高于ＩｇＡ／ＥＡ，接近于８ｇＡ／ＭＡ和ＩｇＡ／ＶＣＡ，特异性高于ＩｇＡ／ＭＡ和ＩｇＡ／ＣＶＡ，接近于ＩｇＡ／ＥＡ。
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| 关 键 词： | EB病毒 IgA／gp125抗体 鼻咽肿瘤 免疫酶法 |
Detection of IgA serum antibodies to Epstein Barr virus gp125 |
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| XUE Shaoli. Detection of IgA serum antibodies to Epstein Barr virus gp125[J]. Chinese Journal of Clinical Laboratory Science, 1998, 16(5): 277-279 |
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| Authors: | XUE Shaoli |
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| Abstract: | EBV capsid antigen gp125 was expressed from cells infected with recombinant vaccinia virus. The presence of IgA antibodies to gp125 in serum from patients wigh NPC, tumors other than NPC and normal individuals were tested by immunoenzymatic method using this recombinant antigen. The data indicate that this method is specific, sensitive and simple for early diagnosis of NPC. |
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| Keywords: | Epstein Barr virus Nasopharyngeal carcinoma IgA antibodies |
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