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A solitary manifestation of mastocytosis in the head and neck
Authors:E. A. M. Mylanus  E. W. J. Wielinga  J. A. P. van de Nes
Affiliation:(1) Department of Otorhinolaryngology, University Hospital of Nijmegen, Philips van Leydenlaan 15, Postbus 9101, 6500 HB Nijmegen, The Netherlands Tel.: +31-24-3614450, Fax: +31-24-3540251, NL;(2) Department of Otorhinolaryngology, Free University Hospital of Amsterdam, The Netherlands, NL;(3) Department of Pathology, University Hospital of Nijmegen, Nijmegen, The Netherlands, NL
Abstract:Solitary mastocytosis in adulthood is a rare finding. Only two such lesions have been reported in the head and neck. We describe a 27-year-old woman who had a 10-year history of a forehead swelling that had fluctuated in size. Light trauma or pressure on the lesion resulted in an increase in its size. A mass was found to be situated just below the galea and was successfully removed surgically using a high forehead lift. Histologically, the specimen contained predominantly mast cells. A systemic mastocytosis was excluded by a multidisciplinary diagnostic approach and measurement of the 24-h urinary excretion of histamine metabolites. After 36 months of follow-up there has been no recurrence. Received: 20 May 1999 / Accepted: 15 July 1999
Keywords:Head and neck solitary lesions  Mastocytosis  Histamine  Surgery
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