Therapeutic challenges in hepatitis C-infected injection drug using patients |
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| Authors: | Curtis L Cooper Edward J Mills |
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| Institution: | (1) Division of Infectious Diseases-The Ottawa Hospital, Associate Professor of Medicine-University of Ottawa Hospital, Ottawa, Canada;(2) Centre for International Health and Human Rights Studies, Toronto, Canada;(3) Faculty of Health Sciences, Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada |
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| Abstract: | Hepatitis C Viral (HCV) infection in the injection drug user (IDU) population is a major medical concern. Concurrent substance
abuse, co-morbid mental health conditions, poor socioeconomic status and a complex treatment protocol that is often incompatible
with the life styles of IDUs combine to account for poor uptake and completion of HCV treatment. This article discusses HCV
antiviral treatment issues relevant to IDUs chronically infected with this virus. The effect of non-injected substances of
abuse on treatment outcome is considered. Priority issues requiring research are discussed. |
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