抗肿瘤药物肺部给药新剂型研究进展 |
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引用本文: | 鲁春青 郑益萍 高亚男 唐景玲. 抗肿瘤药物肺部给药新剂型研究进展[J]. 中国药师, 2018, 0(3): 493-496 |
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作者姓名: | 鲁春青 郑益萍 高亚男 唐景玲 |
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作者单位: | 哈尔滨医科大学药学院 哈尔滨 150086 |
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摘 要: | 摘 要肺癌是最常见的恶性肿瘤之一。抗肿瘤药物静脉给药会造成全身毒性,且疗效低。肺部给药可以使药物聚集于肺部,降低药物在其他器官的分布,从而降低抗肿瘤药物的不良反应。本文着重介绍近年来抗肿瘤药物肺部给药治疗肺癌的新剂型研究进展,为抗肿瘤药物肺部给药的研发提供参考。
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关 键 词: | 肺癌;肺部给药;抗癌药物;脂质体;纳米粒 |
收稿时间: | 2017-10-12 |
修稿时间: | 2017-11-16 |
Research Progress in New Dosage Forms of Anti tumor Drugs for Pulmonary Administration |
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Abstract: | ABSTRACTLung cancer is one of the most common malignancies. Anti tumor drugs with intravenous administration have systemic adverse effects as well as limited efficacy. Drugs can concentrate in lungs after pulmonary administration, which limits the distribution in the other organs and reduces the side effects of anti tumor drugs. The paper focused on the recent progress in the studies on new dosage forms of anti tumor drugs for pulmonary administration for the therapy of lung cancer, so as to provide reference for the development of anti tumor drugs for pulmonary administration. |
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Keywords: | Lung cancer Pulmonary administration Anticancer drugs Liposomes Nanoparticles |
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