噬菌体治疗细菌性疾病的研究进展及发展方向

耐药性"超级细菌"的出现将使我们步入"后抗菌药物时代"。面对日益严重的细菌耐药性,寻找新的抗菌药物及治疗方案已成为目前急需解决的难题。本文通过查阅国内外大量噬菌体临床治疗的成功病例,对噬菌体治疗的优势进行了详尽的阐述,充分说明使用噬菌体裂解耐药菌株是治疗细菌性疾病的有效方法,同时指出噬菌体治疗技术的优势和劣势,并提出了今后的发展方向。

Research progress and development direction of bacteriophage therapy for bacterial infection

The emergence of "superbugs" resistance will bring us into "the post-antimicrobial era". In the face of the increasingly serious bacterial resistance, finding new antimicrobial agents and therapy options has become an urgent problem to be solved. This paper elaborates in detail the advantage of bacteriophage therapy by consulting a large number of successful cases of bacteriophage therapy at home and abroad, fully illustrates that bacteriophage lysis of drug-resistant strains for bacterial disease therapy is an effective method, points out advantage and disadvantage of bacteriophage therapy technology, and puts forward the future development direction.