艾司奥美拉唑在肝胆外科围术期的合理应用分析

目的 了解东方肝胆外科医院（简称"我院"）注射用艾司奥美拉唑钠在肝胆外科围术期应用的合理性,为肝胆手术围术期合理用药提供参考。方法 用回顾性研究方法,通过查阅电子病历、医嘱和检验结果等途径,随机采集了2017年1月至9月300例使用注射用艾司奥美拉唑钠患者的相关信息。300例病例艾司奥美拉唑的使用频次为416次,从给药时间、用药疗程、用法用量、溶剂和应激性溃疡危险因素等方面进行分析。结果 给药时间的合理率是15.67%（47/300）,用药疗程的合理率是10.67%（32/300）,用法的合理率是75%（312/416）,用量的合理率是100%（416/416）,溶媒的合理率为100%（416/416）,具有应激性溃疡危险因素的患者占3.33%（10/300）。结论 我院肝胆外科围术期应用艾司奥美拉唑合理性有待提高,临床药师应加强临床用药教育以提高合理用药水平。

Analysis on rational application of esomeprazole for injection in hepatobiliary perioperative period

Objective To investigate the rationality of esomeprazole for injection in hepatobiliary perioperative period of Eastern Hepatobiliary hospital (hereinafter referred to as our hospital), and to provide reference for the rational drug use in hepatobiliary perioperative. Methods By retrospective investigation, information of 300 randomly patients was collected from Jan to Sep in 2017 with esomeprezole for injection through consulting the electronic medical records, doctor''s advice, inspection, etc. Of the 300 cases of medical records with esomeprazole for injection, the use frequency of esomeprazole were 416, statistical analysis was conducted in terms of the administration time, treatment course, usage and dosage, solvent, and the risk of stress ulcer. Results The rational rate of the administration time was 15.67%(47/300), the treatment course was 10.67%(32/300),the usage was 75%(312/416),dosage and solvent were 100%(416/416),and the ratio of patients with SU risk factors was 3.33%(10/300). Conclusion The rational application of esomeprezole in our hospital still need to be improved. The clinical pharmacists should strengthen clinical medicine education to improve rational drug use in our hospital.