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5岁儿童仿真模体千伏锥束CT模拟剂量测量
引用本文:王美娇,张艺宝,马竟超,丁艳秋,郭文.5岁儿童仿真模体千伏锥束CT模拟剂量测量[J].中华放射医学与防护杂志,2018,38(4):302-306.
作者姓名:王美娇  张艺宝  马竟超  丁艳秋  郭文
作者单位:100088 北京, 中国疾病预防控制中心辐射防护与核安全医学所辐射防护与核应急中国疾病预防控制中心重点实验室,100142 北京大学肿瘤医院暨北京市肿瘤防治研究所放疗科恶性肿瘤发病机制及转化研究教育部重点实验室,136100 公主岭, 吉林国文医院放疗科,100088 北京, 中国疾病预防控制中心辐射防护与核安全医学所辐射防护与核应急中国疾病预防控制中心重点实验室,100088 北京, 中国疾病预防控制中心辐射防护与核安全医学所辐射防护与核应急中国疾病预防控制中心重点实验室
基金项目:国家自然科学基金(11505012);北京市自然科学基金(7172048);首都卫生发展科研专项(首发2018-4-1027)
摘    要:目的 利用热释光探测器(TLD)在CIRS 5岁仿真儿童模体内测量瓦里安千伏锥束CT(kV-CBCT)标准扫描参数下各重要器官剂量,并以此计算有效剂量。方法 挑选一致性在2%以内的TLD并退火。首先基于相同骨盆扫描模式分别用CT电离室和TLD测量CIRS骨盆仿真模体相同体积内的剂量和读数,二者比值即为TLD转换系数;将夹在组织等效插件中的TLD放入儿童模体器官内预留的插孔,在头部、胸部和骨盆3种标准扫描条件模式下,测量器官剂量,并计算有效剂量。结果 TLD转换系数是3.91 mGy/每读数;在头部、胸部和骨盆3种标准扫描条件下,得出全身有效剂量分别是0.63、6.85和19.3 mSv。结论 用CT电离室刻度过的TLD测量kV-CBCT给儿童仿真模体带来的辐射剂量的方法具有可行性。本研究中骨盆扫描条件的有效剂量高于胸部和头部,即该条件预期产生的辐射危害较大,诱发继发性癌症风险较高。

关 键 词:热释光探测器  儿童  千伏锥形束CT  图像引导放射治疗
收稿时间:2018/1/12 0:00:00

Simulated measurement of doses from kilovoltage cone beam CT based on a 5 years old pediatric anthropomorphic phantom
Wang Meijiao,Zhang Yibao,Ma Jingchao,Ding Yanqiu and Guo Wen.Simulated measurement of doses from kilovoltage cone beam CT based on a 5 years old pediatric anthropomorphic phantom[J].Chinese Journal of Radiological Medicine and Protection,2018,38(4):302-306.
Authors:Wang Meijiao  Zhang Yibao  Ma Jingchao  Ding Yanqiu and Guo Wen
Institution:Key Laboratory of Radiological Protection and Nuclear Emergency, China CDC, National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088, China,Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education), Department of Radiotherapy, Peking University Cancer Hospital & Institute, Beijing 100142, China,Department of Radiotherapy, Jilin Guowen Hospital, Gongzhuling 136100, China,Key Laboratory of Radiological Protection and Nuclear Emergency, China CDC, National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088, China and Key Laboratory of Radiological Protection and Nuclear Emergency, China CDC, National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088, China
Abstract:Objective To use thermoluminescense dosimeters (TLDs) to evaluate the radiation doses to various critical organs in the computerized imaging reference systems (CIRS) 5 years old pediatric anthropomorphic phantom result ing from Varian kilovoltage cone beam CT (kV-CBCT) system based on the standard scanning protocols. Effective dose were also calculated based on dose measurement. Methods A batch of TLDs with consistency no larger than 2% were selected and annealed. First, the doses in an anthropomorphic pelvic phantom were measured using a CT chamber and TLDs, respectively, based on the standard pelvic protocols. The ratio of the both measurements is the TLD conversion coefficient. Other TLDs from the same batch were placed between two tissue-equivalent inserts and placed into the pre-drilled organ cavities of the pediatric phantom. By using standard protocols, the organs dose were measured, based on which the corresponding effective doses were calculated. Results The TLD conversion coefficient was 3.91 mGy/per reading. By using the standard head, low-dose thorax, pelvis protocol, the whole body effective dose was 0.63, 6.85 and 19.3 mSv, respectively. Conclusions It is feasible for using the CT chamber-calibrated TLDs to measure the radiation doses from kV-CBCT to pediatric anthropomorphic phantom. The effective dose in pelvic protocol was higher than in thorax and head protocol, indicating that the pelvic protocol has a penitential to lead to larger radiation damage and higher risk of secondary cancer.
Keywords:Thermoluminescent dosimeter (TLD)  Pediatric  Kilo-voltage cone beam CT  Image-guided radiotherapy
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