| 药物相互作用致环孢素不良反应分析及药学监护 |
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| 引用本文： | 常馨予,郭桂明,刘洋,韩丽娟,车晓平,范峥.药物相互作用致环孢素不良反应分析及药学监护[J].药学实践杂志,2018,36(4):365-368. |
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| 作者姓名： | 常馨予 郭桂明 刘洋 韩丽娟 车晓平 范峥 |
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| 作者单位： | 首都医科大学附属北京中医医院临床药学科, 北京 100038,首都医科大学附属北京中医医院临床药学科, 北京 100038,首都医科大学附属北京中医医院临床药学科, 北京 100038,首都医科大学附属北京中医医院临床药学科, 北京 100038,首都医科大学附属北京中医医院临床药学科, 北京 100038,首都医科大学附属北京中医医院临床药学科, 北京 100038 |
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| 摘 要： | 目的 探讨临床药师在药物相互作用致不良反应的临床判断和治疗中所发挥的作用。方法 通过临床药师对因停用抗结核药物致环孢素神经系统不良反应的病例分析，探讨环孢素与双手无力伴震颤不良反应的相关性，解析抗结核药物对环孢素血药浓度的影响机制，最后给出关于药物相互作用致不良反应的建议，协助临床医师处理不良反应。结果 临床药师通过自身专业特长，及时发现引起不良反应的原因，协助医生调整患者给药方案，患者病情得以好转。结论 临床药师关注不良反应，协助医师保障临床用药安全。
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| 关 键 词： | 环孢素 不良反应 合理用药 |
| 收稿时间： | 2017/9/11 0:00:00 |
| 修稿时间： | 2018/3/5 0:00:00 |
Analysis and pharmaceutical care of the adverse reaction of cyclosporine induced by drug interaction |
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| CHANG Xinyu,GUO Guiming,LIU Yang,HAN Lijuan,CHE Xiaoping and FAN Zheng.Analysis and pharmaceutical care of the adverse reaction of cyclosporine induced by drug interaction[J].The Journal of Pharmaceutical Practice,2018,36(4):365-368. |
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| Authors: | CHANG Xinyu GUO Guiming LIU Yang HAN Lijuan CHE Xiaoping and FAN Zheng |
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| Institution: | Department of Clinical Pharmacy, Beijing Traditional Chinese Medicine Hospital Affiliated to Capital Medical University, Beijing 100038, China,Department of Clinical Pharmacy, Beijing Traditional Chinese Medicine Hospital Affiliated to Capital Medical University, Beijing 100038, China,Department of Clinical Pharmacy, Beijing Traditional Chinese Medicine Hospital Affiliated to Capital Medical University, Beijing 100038, China,Department of Clinical Pharmacy, Beijing Traditional Chinese Medicine Hospital Affiliated to Capital Medical University, Beijing 100038, China,Department of Clinical Pharmacy, Beijing Traditional Chinese Medicine Hospital Affiliated to Capital Medical University, Beijing 100038, China and Department of Clinical Pharmacy, Beijing Traditional Chinese Medicine Hospital Affiliated to Capital Medical University, Beijing 100038, China |
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| Abstract: | Objective To explore the role of clinical pharmacists in the clinical judgment and treatment of adverse drug reactions induced by drug interactions. Methods The correlation between cyclosporine and adverse effects of tremor in two hands were investigated by clinical pharmacists. The mechanism of the effect of anti-tuberculosis drugs on cyclosporine blood concentration was analyzed. Finally, suggestions on adverse reactions to drug interactions were given to assist clinicians in dealing with adverse reactions. Results The causes of adverse reactions were found out in time by the clinical pharmacists from their professional expertise. The clinical pharmacists assisted the doctor to adjust the patient''s regimen. The patient''s condition would be improved. Conclusion Clinical pharmacists could help doctors to ensure the safety of clinical medication through paying attention to adverse reactions. |
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| Keywords: | cyclosporine adverse reactions rational use of drugs |
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