| 他克莫司降压物质检查法的研究 |
| |
| 引用本文： | 贾首前,胡萌萌,南荣华,徐长根,张鹏. 他克莫司降压物质检查法的研究[J]. 中国药品标准, 2018, 19(6): 465-468 |
| |
| 作者姓名： | 贾首前 胡萌萌 南荣华 徐长根 张鹏 |
| |
| 作者单位： | 陕西省食品药品监督检验研究院,陕西省食品药品监督检验研究院,陕西省食品药品监督检验研究院,陕西省食品药品监督检验研究院,陕西省食品药品监督检验研究院 |
| |
| 摘 要： | 目的:建立他克莫司降压物质检查方法,提高其临床用药安全。方法:通过对他克莫司与组胺对照品引起麻醉猫血压下降程度比较研究,确定他克莫司降压物质检查法的限值。结果：降压物质检查项限值定为0.5 mg.kg-1,按此限值检查结果符合规定。结论：建立的他克莫司降压物质检查法方法可行。
|
| 关 键 词： | 他克莫司 降压物质检查法 限值 |
| 收稿时间： | 2018-06-13 |
| 修稿时间： | 2018-11-30 |
Study on the Depressor Substance Test of tacrolimus |
| |
| Affiliation: | Shaanxi Provincial Institute for Food and Drug Control,Shaanxi Provincial Institute for Food and Drug Control,Shaanxi Provincial Institute for Food and Drug Control,Shaanxi Provincial Institute for Food and Drug Control,Shaanxi Provincial Institute for Food and Drug Control |
| |
| Abstract: | ABSTRACT: OBJECTIVE To establish the depressor substance test of tacrolimus.METHODS By investigating the regulating action of tacrolimus and histamine for the blood pressure in the anesthetic cats, the limit values were determined for the depressor substance test of tacrolimus. RESULTS The limit of depressor substance test was defined as 0.5mg?kg-1.CONCLUSION The setted method for the depressor substance test of tacrolimus will be available. |
| |
| Keywords: | tacrolimus depressor dubstance test limit |
|
| 点击此处可从《中国药品标准》浏览原始摘要信息 |
|
点击此处可从《中国药品标准》下载全文 |
|
